Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section

Description

The purpose of this collaborative CTSA (Clinical and Translational Science Award) application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in breastfeeding mothers and their infants

Conditions

Cesarean Section Complications, Opioid Use

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Study Overview

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Study Details

Study overview

The purpose of this collaborative CTSA (Clinical and Translational Science Award) application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in breastfeeding mothers and their infants

Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section

Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section

Condition
Cesarean Section Complications
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

UPMC Magee Women's Hospital, Pittsburgh, Pennsylvania, United States, 15213

Pittsburgh

University of Pittsburgh, Pittsburgh, Pennsylvania, United States, 15260

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Health conditions including uncontrolled diabetes (gestational or pre-existing) or hypertension (pre-eclampsia, eclampsia, or chronic)
  • 2. Any history of opioid misuse before or during pregnancy-per self-report and clinical notes
  • 3. Preoperative severe pain and opioid use/misuse, allergy to oxycodone
  • 4. Allergy to oxycodone
  • 5. Significant neurological disorders, liver and renal diseases

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Senthil Sadhasivam,

Senthilkumar Sadhasivam, MD, MPH, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

2026-10-30