Meaning-Centered Pain Coping Skills Training for Cancer Pain

Description

This study is a randomized controlled trial of a psychosocial pain management intervention called, Meaning-Centered Pain Coping Skills Training (MCPC). Patients with advanced solid tumor cancer and pain interference (N=210) will be randomized to MCPC or a standard care control condition. Patient-reported outcomes will be assessed at baseline and 8- and 12-week follow-ups. The risk and safety issues in this trial are low and limited to those common to a psychosocial intervention (e.g., loss of confidentiality).

Conditions

Advanced Solid Tumor, Pain

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Study Overview

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Study Details

Study overview

This study is a randomized controlled trial of a psychosocial pain management intervention called, Meaning-Centered Pain Coping Skills Training (MCPC). Patients with advanced solid tumor cancer and pain interference (N=210) will be randomized to MCPC or a standard care control condition. Patient-reported outcomes will be assessed at baseline and 8- and 12-week follow-ups. The risk and safety issues in this trial are low and limited to those common to a psychosocial intervention (e.g., loss of confidentiality).

Meaning-Centered Pain Coping Skills Training: A Randomized Controlled Trial of a Psychosocial Intervention for Advanced Cancer Patients

Meaning-Centered Pain Coping Skills Training for Cancer Pain

Condition
Advanced Solid Tumor
Intervention / Treatment

-

Contacts and Locations

Durham

Duke Cancer Center, Durham, North Carolina, United States, 27710

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Stage IV solid tumor cancer diagnosis
  • * Eastern Cooperative Oncology Group (ECOG) performance status of 2 or lower
  • * At least one clinical pain severity rating \> 0 out of 10 in past month
  • * At least moderate pain interference (8-item Patient-Reported Outcomes Measurement Information System \[PROMIS\] Pain Interference T-score \>/= 55) in the past week at telephone screening
  • * Ability to speak and read in English
  • * Age \>/= 18 years.
  • * Significant cognitive impairment as indicated in medical chart or during telephone screening
  • * Serious untreated mental illness
  • * Primary brain cancer diagnosis
  • * Previous engagement in Pain Coping Skills Training or Meaning-Centered Psychotherapy
  • * Enrollment in hospice at screening

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Duke University,

Joseph G Winger, PhD, PRINCIPAL_INVESTIGATOR, Duke University

Study Record Dates

2026-03-26