Cannabis' Impact on Alcohol Consumption

Description

This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consumed. Cannabis will be administered simultaneously with an alcohol-priming dose or alcohol placebo. The study will enroll up to 350 nontreatment-seeking heavy episodic alcohol drinkers who use cannabis weekly.

Conditions

Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder

Study Overview

Study Details

Study overview

This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which participants choose either to drink or receive monetary reinforcement for drinks not consumed. Cannabis will be administered simultaneously with an alcohol-priming dose or alcohol placebo. The study will enroll up to 350 nontreatment-seeking heavy episodic alcohol drinkers who use cannabis weekly.

Cannabis' Impact on Alcohol Consumption: Integrating Laboratory and Ecological Momentary Assessment Methods

Cannabis' Impact on Alcohol Consumption

Condition
Alcohol Drinking
Intervention / Treatment

-

Contacts and Locations

Providence

Brown University, Providence, Rhode Island, United States, 02912

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 21 to 50
  • * English-speaking
  • * cannabis smoking in past two months
  • * heavy drinking in past two months
  • * in good physical health and weighing \< 250 lbs
  • * zero breath alcohol at each visit
  • * positive pregnancy test
  • * nursing
  • * positive urine toxicology screen for drugs other than cannabis
  • * interest to quit or receive treatment for cannabis or alcohol use

Ages Eligible for Study

21 Years to 50 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Brown University,

Jane Metrik, PhD, PRINCIPAL_INVESTIGATOR, Brown University

Study Record Dates

2027-03-31