Cerebellum and Autism: Regional Specialization for Social and Executive Functions

Description

The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.

Conditions

Autism, Autism Spectrum Disorder

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Study Overview

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Study Details

Study overview

The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.

Cerebellum and Autism: Regional Specialization for Social and Executive Functions

Cerebellum and Autism: Regional Specialization for Social and Executive Functions

Condition
Autism
Intervention / Treatment

-

Contacts and Locations

Washington

American University, Washington, District of Columbia, United States, 20016

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Aged 18-35
  • * Able to provide written, informed consent
  • * NIH Toolbox age-adjusted Cognitive Function Composite standard score ≥ 85
  • * Native English speaker
  • * Right-handed
  • * Not pregnant
  • * Able to attend all study sessions
  • * Pass safety screening for MRI and neuromodulation (e.g. no metal in body, implanted devices, history of seizure, claustrophobia)
  • * Prior research-reliable diagnosis of autism spectrum disorder (ASD) Or
  • * Meet DSM-5 criteria for ASD confirmed with ADOS-2 via research-reliable clinical assessment
  • * Age \<18 or \>35
  • * NIH Toolbox age-adjusted Cognitive Function Composite standard score \< 85
  • * Contraindications for MRI or neuromodulation with tDCS (e.g. metal in body, pacemaker or other implanted device, history of seizure, claustrophobia)
  • * Current or prior history of neurological or neurodevelopmental condition or brain injury
  • * Psychotropic medication
  • * Pregnancy
  • * Age \<18 or \>35
  • * Participants with a legal authorized representative
  • * NIH Toolbox age-adjusted Cognitive Function Composite standard score \< 85
  • * Contraindications for MRI or neuromodulation with tDCS (e.g. metal in body, pacemaker or other implanted device, history of seizure, claustrophobia)
  • * Pregnancy

Ages Eligible for Study

18 Years to 35 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

American University,

Catherine Stoodley, D.Phil., PRINCIPAL_INVESTIGATOR, American University

Study Record Dates

2024-12-31