Long Haul COVID Rehabilitation & Recovery Research Program

Description

The purpose of the study is to assess the physiologic, immunologic, and mental health effects of a rehabilitation program on patients with Long Haul COVID (LHC).

Conditions

Post-Acute COVID-19 Syndrome

Study Overview

Study Details

Study overview

The purpose of the study is to assess the physiologic, immunologic, and mental health effects of a rehabilitation program on patients with Long Haul COVID (LHC).

Long Haul COVID Rehabilitation & Research Program

Long Haul COVID Rehabilitation & Recovery Research Program

Condition
Post-Acute COVID-19 Syndrome
Intervention / Treatment

-

Contacts and Locations

Torrance

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States, 90509

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Long Haul COVID Infection (Documented by PCR or patient report)
  • * Age \>= 18 years old.
  • * At least 12 weeks since the initial COVID Infection.
  • * One or more of the following symptom/signs: Fatigue, Dyspnea, Exercise Intolerance, Post Exertional Malaise and/or Difficulty Breathing.
  • * Able to perform a cardiopulmonary exercise test.
  • * Patients is not able to perform technically acceptable pulmonary function tests and symptom-limited cardiopulmonary cycle ergometry tests.
  • * Patients who desaturate to SpO2 \<80% on screening incremental exercise testing.
  • * Patients who have completed a pulmonary rehabilitation program in the six weeks prior to the screening visit or patients who are currently in a pulmonary rehabilitation program.
  • * Patients who have taken an investigational drug within one month or six half-lives (whichever is greater) prior to screening visit (Visit 1).
  • * Pregnant or nursing women.
  • * Women of childbearing potential who are not using a highly effective method of birth control. Female patients will be considered of childbearing potential unless surgically sterilized by hysterectomy or bilateral tubal ligation, or post-menopausal for at least two years.
  • * Patients who are currently participating in another interventional study.
  • * Malignancy for which the patient has undergone resection, radiation therapy, or chemotherapy within the last 2 years
  • * Any other significant disease than COVID which, in the opinion of the investigator, may i) put the patient at risk because of participation in the study, ii) influence the results of the study (e.g. Insulin or testosterone therapy, systemic corticosteroids, HIV, etc), iii) cause concern regarding the patient's ability to participate in the study.

Ages Eligible for Study

18 Years to 90 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center,

Study Record Dates

2025-02-02