RECRUITING

Harm Reduction in HIV Primary Care for PLWH Who Use Drugs

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

People living with HIV (PLWH) who use drugs experience significant health disparities including lower rates of retention in HIV care and higher rates of unsuppressed viral load, resulting in secondary infections and increased mortality. The proposed study will used mixed methods to explore (a) the relationship between healthcare providers' attitudes towards working with PLWH who use drugs and providers' acceptance and practice of structural and relational harm reduction; (b) the degree to which relational harm reduction moderates the effect of intersectional stigma experienced in healthcare settings on patients' perceptions of their relationship with providers; (c) the degree to which structural HR moderates the relationship between the patient-provider relationship and clinical outcomes, and (d) whether patient-perceived HR approaches to care are directly associated with HIV clinical outcomes. The study will also use these findings to inform the development and pre-testing of an intervention to operationalize harm reduction in HIV clinical settings, using stakeholder-engaged and human-centered design approaches, presenting a novel path to reducing HIV health inequities for PLWH who use drugs.

Official Title

Impact of Harm Reduction Care in HIV Clinical Settings on Stigma and Health Outcomes

Quick Facts

Study Start:2022-04-20
Study Completion:2026-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05404750

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Providers' Inclusion Criteria
  2. * Working at one of our 3 study sites (UPMC HIV/AIDS Program, Positive Health Clinic, or 1917 Clinic) or one of their partner sites offering substance use treatment (Internal Medicine Recovery Engagement Program, Center for Inclusion Health, or UAB's Outpatient-Based Opioid Treatment Clinic) for at least one year
  3. * Providing service or care to PLWH or people who use drugs at high risk for HIV acquisition
  4. * Working in one of the following positions: front desk/patient engagement, social worker, nurse, medical assistant, advanced practice provider, or physician
  5. * Able to verbally consent, read, and speak English
  6. 2. Patient Inclusion Criteria
  7. * Living with HIV
  8. * Age 18 or older
  9. * Able to verbally consent, read, and speak English
  10. * Receiving HIV medical care from one of the study sites for at least one year
  11. * Lifetime or recent use (past 3 months) of illicit substances (excluding marijuana) or prescription drugs for non-medical reasons in accordance with the NIDA-Modified ASSIST 2.0.
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Mary Hawk, DrPH
CONTACT
412-648-2342
meh96@pitt.edu
Stephanie Creasy, MPH
CONTACT
412-624-7000
stc69@pitt.edu

Principal Investigator

Mary Hawk, DrPH
PRINCIPAL_INVESTIGATOR
University of Pittsburgh
Emma Kay, PhD
PRINCIPAL_INVESTIGATOR
Birmingham AIDS Outreach

Study Locations (Sites)

University of Alabama at Birmingham
Birmingham, Alabama, 35222
United States
Birmingham AIDS Outreach
Birmingham, Alabama, 35233
United States
Allegheny Health Network Research Institute
Pittsburgh, Pennsylvania, 15212
United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213
United States

Collaborators and Investigators

Sponsor: University of Pittsburgh

  • Mary Hawk, DrPH, PRINCIPAL_INVESTIGATOR, University of Pittsburgh
  • Emma Kay, PhD, PRINCIPAL_INVESTIGATOR, Birmingham AIDS Outreach

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-04-20
Study Completion Date2026-06-30

Study Record Updates

Study Start Date2022-04-20
Study Completion Date2026-06-30

Terms related to this study

Keywords Provided by Researchers

  • Harm Reduction
  • Patient-Provider Relationship

Additional Relevant MeSH Terms

  • Human Immunodeficiency Virus
  • Substance Use
  • Stigma, Social