RECRUITING

Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color. Through a split-wound study design, patients undergoing standard elliptical excisions at least 3 cm in length will receive each suture type. Measurements of dyspigmentation and scarring will be made at 7 days (for the head and neck), 10 days (for the trunk and extremities), and 3 months for all locations.

Official Title

Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color: A Prospective, Randomized Split-wound Study

Quick Facts

Study Start:2022-10-01
Study Completion:2025-09-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05408117

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Age 18 years or older
  2. 2. Undergoing dermatologic surgery with planned standard elliptical excision with wound length of 3 cm or greater. Benign and malignant lesions will be included, including those that have undergone Mohs micrographic surgery prior to standard linear closure. All body sites will be included.
  3. 3. Able to give informed consent
  4. 4. Able to return for 3 month follow up
  5. 5. New Immigration Scale (NIS) skin color 4 or greater - The NIS is an 11 point scale, ranging from zero to 10, with zero representing albinism and 10 representing the darkest possible skin.
  1. 1. High-tension closures not amenable to 5-0 simple running epidermal sutures
  2. 2. Known allergy to suture material
  3. 3. Pregnant

Contacts and Locations

Study Contact

Melissa Pugliano-Mauro, MD
CONTACT
412-784-7350
puglianomauroma@upmc.edu

Principal Investigator

Melissa Pugliano-Mauro, MD
PRINCIPAL_INVESTIGATOR
University of Pittsburgh Medical Center

Study Locations (Sites)

UPMC Presbyterian
Pittsburgh, Pennsylvania, 15213
United States
UPMC St. Margaret
Pittsburgh, Pennsylvania, 15215
United States
UPMC Shadyside Place
Pittsburgh, Pennsylvania, 15232
United States

Collaborators and Investigators

Sponsor: Melissa Pugliano-Mauro

  • Melissa Pugliano-Mauro, MD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-10-01
Study Completion Date2025-09-01

Study Record Updates

Study Start Date2022-10-01
Study Completion Date2025-09-01

Terms related to this study

Keywords Provided by Researchers

  • skin of color
  • split-wound
  • polypropylene
  • fast gut
  • pigmentary disturbance

Additional Relevant MeSH Terms

  • Scar