RECRUITING

Assessment of the Ocular Microbiome in Health and Disease

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of this application is to illustrate the core constituents of the ocular surface microbiome, describe factors that promote colonization, and assess the ocular microbiome's role in the health of the anterior segment. We will conduct a prospective, observational cohort study, including a longitudinal analysis of the ocular microbiome in adults.

Official Title

Assessment of the Ocular Microbiome in Health and Disease

Quick Facts

Study Start:2023-09-07
Study Completion:2027-12-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05414994

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18 years of age or older
  2. * Provide informed consent
  3. * Cohort A - normal eyes with no ocular disease
  4. * Cohort B - primary open angle glaucoma/Ocular hypertension defined as mild glaucoma which is well controlled with no more than one drop of prostaglandin use daily for the past 6 months
  5. * Cohort C - non-infectious keratopathy not using any prescription medication (OTC artificial tears are acceptable)
  6. * Cohort D - Dry AMD (age related macular degeneration)
  7. * Cohort E - Wet AMD
  8. * Cohort F - diabetic retinopathy
  1. * Prior ocular disease either of the anterior or posterior segment
  2. * Any medical comorbidities except well controlled DH and HTN
  3. * Unable to follow up with study procedures as described

Contacts and Locations

Study Contact

saige Wilkins
CONTACT
6159361474
saige.wilkins@vumc.org

Study Locations (Sites)

Vanderbilt University Medical Center
Nashville, Tennessee, 37232
United States

Collaborators and Investigators

Sponsor: Vanderbilt University Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-09-07
Study Completion Date2027-12-30

Study Record Updates

Study Start Date2023-09-07
Study Completion Date2027-12-30

Terms related to this study

Additional Relevant MeSH Terms

  • Microbial Colonization
  • Eye Diseases
  • Ophthalmopathy