RECRUITING

Immune Signature Analysis of Disease Progression in Post Immunotherapy Lung Cancer Patients

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to examine the association between ctDNA/immune biomarkers and disease progression in patients who, at immunotherapy discontinuation, have completed at least 20 of an anticipated 24 months of immune checkpoint inhibitor monotherapy or immune checkpoint inhibitor combination chemotherapy for mNSCLC.

Official Title

A Prospective Study of Immune Signatures in Metastatic Non-Small Cell Lung Cancer (mNSCLC) Patients At Completion of Immune Checkpoint Inhibitor Treatment Either As Monotherapy or in Combination with Chemotherapy in the First Line Setting

Quick Facts

Study Start:2023-01-17
Study Completion:2035-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05415358

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Alicia Patrick
CONTACT
(980) 292-1746
Alicia.Patrick@atriumhealth.org

Principal Investigator

Kathryn Mileham, MD
PRINCIPAL_INVESTIGATOR
Atrium Health Levine Cancer

Study Locations (Sites)

Atrium Health Levine Cancer
Charlotte, North Carolina, 28204
United States
Atrium Health Wake Forest Baptist Comprehensive Cancer Center
Winston-Salem, North Carolina, 27157
United States

Collaborators and Investigators

Sponsor: Wake Forest University Health Sciences

  • Kathryn Mileham, MD, PRINCIPAL_INVESTIGATOR, Atrium Health Levine Cancer

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-17
Study Completion Date2035-09

Study Record Updates

Study Start Date2023-01-17
Study Completion Date2035-09

Terms related to this study

Additional Relevant MeSH Terms

  • Lung Cancer, Nonsmall Cell