The investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 40-50% in painful non-spinal bone metastases. Additionally, the investigators hypothesize that utilizing a fractionation scheme with an escalated biologically equivalent dose (BED) will result in a higher proportion of participants responding to treatment, and will also lead to more durable responses. Furthermore, the investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 35-45% in painful non-bone metastases
Neoplasm Metastases, Metastases, Neoplasm
The investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 40-50% in painful non-spinal bone metastases. Additionally, the investigators hypothesize that utilizing a fractionation scheme with an escalated biologically equivalent dose (BED) will result in a higher proportion of participants responding to treatment, and will also lead to more durable responses. Furthermore, the investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 35-45% in painful non-bone metastases
Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metas
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RWJBarnabas Health - Robert Wood Johnson University Hospital, Hamilton, New Jersey, United States, 08690
RWJBarnabas Health - Monmouth Medical Center Southern Campus, Lakewood, New Jersey, United States, 08701
RWJBarnabas Health - Saint Barnabas Medical Center, Livingston, New Jersey, United States, 10457
Robert Wood Johnson University Hospital, New Brunswick, New Jersey, United States, 08901
Cancer Institute of New Jersey, New Brunswick, New Jersey, United States, 08903
RWJBarnabas Health - Robert Wood Johnson University Hospital, Somerset, New Jersey, United States, 08876
RWJBarnabas Health - Community Medical Center, Toms River, New Jersey, United States, 08755
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to
ALL
No
Rutgers, The State University of New Jersey,
Matthew P Deek, MD, PRINCIPAL_INVESTIGATOR, Rutgers Cancer Institute of New Jersey
2024-04-01