Role of Sleep Reactivity in Shift Work Disorder

Description

The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD). The primary hypothesis is that those with high sleep reactivity will show persistent SWD symptoms after experimental reduction of circadian misalignment, which will then be mitigated with CBT.

Conditions

Shift-work Disorder

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Study Overview

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Study Details

Study overview

The purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD). The primary hypothesis is that those with high sleep reactivity will show persistent SWD symptoms after experimental reduction of circadian misalignment, which will then be mitigated with CBT.

Sleep Reactivity as a Novel Mechanism in Shift Work Disorder

Role of Sleep Reactivity in Shift Work Disorder

Condition
Shift-work Disorder
Intervention / Treatment

-

Contacts and Locations

Novi

Henry Ford Columbus Medical Center, Novi, Michigan, United States, 48377

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Participants must be working a fixed nightshift schedule, operationalized as: a) working at least three night shifts a week, b) shifts must begin between 18:00 and 02:00, and last between 8 to 12 hours, and c) must also plan to maintain the nightshift schedule for the duration of the study
  • * Participants must have Shift Work Disorder, which will be diagnosed based on ICSD-3 criteria
  • * Participants must show circadian misalignment, operationalized as a baseline melatonin onset between 18:00 and 01:00.
  • * Participants must be at least 18 years old
  • * Insomnia disorder or excessive sleepiness predating the onset of shift work
  • * Termination of nightshift schedule
  • * Presence of other sleep disorders (e.g. obstructive sleep apnea, narcolepsy) determined by standard clinical polysomnography
  • * Diagnosis of bipolar disorder
  • * History of neurological disorders determined by self-report and medical history
  • * Pregnancy
  • * Alcohol use disorder
  • * Illicit drug use via self-report and urine drug screen if reasonable suspicion to test

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Henry Ford Health System,

Study Record Dates

2027-10-01