eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Description

This randomized non-inferiority study will use a 2x2 design where traditional standard-of-care pre-test (visit 1) and post-test (visit 2: disclosure) counseling delivered by a genetic counselor are replaced with a self-directed web-based eHealth intervention to provide critical data to inform optimal ways to deliver clinical genetic testing in eligible individuals, while maintaining quality of care and favorable cognitive, affective and behavioral outcomes.

Conditions

Cancer

Study Overview

Study Details

Study overview

This randomized non-inferiority study will use a 2x2 design where traditional standard-of-care pre-test (visit 1) and post-test (visit 2: disclosure) counseling delivered by a genetic counselor are replaced with a self-directed web-based eHealth intervention to provide critical data to inform optimal ways to deliver clinical genetic testing in eligible individuals, while maintaining quality of care and favorable cognitive, affective and behavioral outcomes.

A Randomized Hybrid Type I Effectiveness-Implementation Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

Condition
Cancer
Intervention / Treatment

-

Contacts and Locations

Philadelphia

Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania, United States, 19104

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18 years of age or older
  • * Speak and understand English
  • * Male or Female
  • * No prior germline genetic testing
  • * Meet current National Comprehensive Cancer Network (NCCN) guidelines for germline genetic testing
  • * Uncorrected or uncompensated hearing and/or vision impairment
  • * Uncorrected or uncompensated speech defects
  • * Uncontrolled psychiatric/mental condition or severe physical, neurological or cognitive deficits rendering individual unable to understand study goals and tasks

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Abramson Cancer Center at Penn Medicine,

Angela R Bradbury, MD, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Study Record Dates

2026-01