RECRUITING

Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety

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Conditions

Anxiety DisordersTraumaGeneralized Anxiety DisorderPanic DisorderAgoraphobiaIllness Anxiety DisorderSocial Anxiety DisorderPosttraumatic Stress DisorderAcute Stress DisorderAdjustment Disorder With Anxious MoodPsychoeducationRespiratory trainingTransdiagnosticIntervention

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Purpose of the Research: The primary aim of the proposed study is to conduct a randomized parallel-group 2-arm clinical trial investigating capnometry-guided respiratory intervention (CGRI) for pathological anxiety. CGRI aims to raise end-tidal CO2 levels thereby lowering hyperventilation-induced respiratory alkalosis and its associated fear-eliciting somatic reactions. Psycho-education about anxiety and its effects (PsyEd) will serve as a credible control comparator.

Official Title

Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety: A Randomized Clinical Trial

Quick Facts

Study Start:2022-08-22
Study Completion:2027-05
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05427708

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Clinically elevated anxiety as indicated by an eight or higher on the Overall Anxiety Severity and Impairment Scale (OASIS).
  2. 2. Meets DSM-5 criteria for one or more of the following anxiety or trauma-related disorders as their "primary" mental disorder:
  3. * Generalized Anxiety Disorder
  4. * Panic Disorder
  5. * Health Anxiety
  6. * Agoraphobia
  7. * Social Anxiety Disorder
  8. * Posttraumatic Stress Disorder
  9. * Acute Stress Disorder
  10. * Adjustment Disorder with primary anxious mood
  11. * Anxiety disorder not otherwise specified
  12. 3. No current use of psychotropic medications or stable on current medications for at least 6 weeks
  13. 4. Age 18+.
  14. 5. Able to arrange transportation to our laboratory for study appointments.
  15. 6. Fluent in English.
  1. 1. No history of medical conditions that would contraindicate participation in fear-provocation or respiratory challenges, including:
  2. * Cardiovascular or respiratory disorders
  3. * High blood pressure
  4. * Epilepsy
  5. * Strokes
  6. * Seizures
  7. * History of fainting
  8. * Pregnant or lactating
  9. 2. Not currently receiving other psychological treatment for anxiety.
  10. 3. No history of a suicide attempt within the past 6 months.
  11. 4. No history of psychosis within the past 6 months.
  12. 5. No history of moderate to severe alcohol or substance use disorder (with the exception of nicotine) within the past 3 months.
  13. 6. Does not endorse COVID-19 symptoms during the screening phase.

Contacts and Locations

Study Contact

Michael J Telch, PhD
CONTACT
512-814-5480
telch@austin.utexas.edu
Shristi Saraff
CONTACT
utinterventionstudy@gmail.com

Study Locations (Sites)

University of Texas at Austin
Austin, Texas, 78712
United States

Collaborators and Investigators

Sponsor: University of Texas at Austin

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-08-22
Study Completion Date2027-05

Study Record Updates

Study Start Date2022-08-22
Study Completion Date2027-05

Terms related to this study

Keywords Provided by Researchers

  • Psychoeducation
  • Respiratory training
  • Transdiagnostic
  • Intervention

Additional Relevant MeSH Terms

  • Anxiety Disorders
  • Trauma
  • Generalized Anxiety Disorder
  • Panic Disorder
  • Agoraphobia
  • Illness Anxiety Disorder
  • Social Anxiety Disorder
  • Posttraumatic Stress Disorder
  • Acute Stress Disorder
  • Adjustment Disorder With Anxious Mood