Activity, Adiposity, and Appetite in Adolescents 2 Intervention

Description

The objective of the study is to quantify the relationship between physical activity, metabolic function, and appetite in adolescents. To do this we will test our working hypothesis that high levels of regular moderate-to-vigorous physical activity (MVPA), as opposed to body weight status, results in a metabolic phenotype consisting of enhanced metabolic function and proper regulation of appetite. We will randomly assigning sedentary overweight/obese adolescents (N=44) to either a control or structured-exercise group for three months.

Conditions

Obesity, Energy Balance, Appetite, Metabolism, Insulin Sensitivity

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Study Overview

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Study Details

Study overview

The objective of the study is to quantify the relationship between physical activity, metabolic function, and appetite in adolescents. To do this we will test our working hypothesis that high levels of regular moderate-to-vigorous physical activity (MVPA), as opposed to body weight status, results in a metabolic phenotype consisting of enhanced metabolic function and proper regulation of appetite. We will randomly assigning sedentary overweight/obese adolescents (N=44) to either a control or structured-exercise group for three months.

Activity, Adiposity, and Appetite in Adolescents 2 Intervention

Activity, Adiposity, and Appetite in Adolescents 2 Intervention

Condition
Obesity
Intervention / Treatment

-

Contacts and Locations

Kansas City

Children's Mercy Kansas City, Kansas City, Missouri, United States, 64108

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Tanner Stage III-V, as determined via self-assessment
  • * Non-smoking
  • * Not currently involved in any other research study
  • * No meds that may alter metabolism
  • * Sedentary (\<60 min/day exercise)
  • * Willing to participate in an exercise program
  • * BMI \<5th percentile or \>99th percentile for age and sex
  • * Weight not stable
  • * Restrained eater (\>13 on the restraint section of the three-factor eating questionnaire; Current/past diagnosis of an eating disorder.
  • * Self-reported medical conditions (including, but not limited to, diabetes, Crohn's disease, etc.) that may affect adherence to the protocol, exercising safely, or alter metabolism
  • * Taking medications know to affect metabolism (e.g. thyroid medication, β-blockers, or stimulants).
  • * Gave birth in the past 12 months or \<6 months post-lactation.
  • * Active (\>60 min/day exercise)
  • * Not willing to participate in an exercise program

Ages Eligible for Study

14 Years to 17 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Children's Mercy Hospital Kansas City,

Study Record Dates

2024-12-31