RECRUITING

Activity, Adiposity, and Appetite in Adolescents 2 Intervention

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of the study is to quantify the relationship between physical activity, metabolic function, and appetite in adolescents. To do this we will test our working hypothesis that high levels of regular moderate-to-vigorous physical activity (MVPA), as opposed to body weight status, results in a metabolic phenotype consisting of enhanced metabolic function and proper regulation of appetite. We will randomly assigning sedentary overweight/obese adolescents (N=44) to either a control or structured-exercise group for three months.

Official Title

Activity, Adiposity, and Appetite in Adolescents 2 Intervention

Quick Facts

Study Start:2022-09-14
Study Completion:2024-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05443347

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:14 Years to 17 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Tanner Stage III-V, as determined via self-assessment
  2. * Non-smoking
  3. * Not currently involved in any other research study
  4. * No meds that may alter metabolism
  5. * Sedentary (\<60 min/day exercise)
  6. * Willing to participate in an exercise program
  1. * BMI \<5th percentile or \>99th percentile for age and sex
  2. * Weight not stable
  3. * Restrained eater (\>13 on the restraint section of the three-factor eating questionnaire; Current/past diagnosis of an eating disorder.
  4. * Self-reported medical conditions (including, but not limited to, diabetes, Crohn's disease, etc.) that may affect adherence to the protocol, exercising safely, or alter metabolism
  5. * Taking medications know to affect metabolism (e.g. thyroid medication, β-blockers, or stimulants).
  6. * Gave birth in the past 12 months or \<6 months post-lactation.
  7. * Active (\>60 min/day exercise)
  8. * Not willing to participate in an exercise program

Contacts and Locations

Study Contact

Robin P Shook
CONTACT
2144488366
rpshook@cmh.edu
Paige Posson, MS, RD
CONTACT
816-234-9230
pmposson@cmh.edu

Study Locations (Sites)

Children's Mercy Kansas City
Kansas City, Missouri, 64108
United States

Collaborators and Investigators

Sponsor: Children's Mercy Hospital Kansas City

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-09-14
Study Completion Date2024-12-31

Study Record Updates

Study Start Date2022-09-14
Study Completion Date2024-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Obesity
  • Energy Balance
  • Appetite
  • Metabolism
  • Insulin Sensitivity