RECRUITING

Genomic Predictors of Recurrent Pregnancy Loss

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The overall goals of this proposal are to determine the genetic architecture of recurrent pregnancy loss (RPL) and to discover genomic predictors of RPL.

Official Title

Large Scale Genome Sequencing and Integrative Analyses to Define Genomic Predictors of Recurrent Pregnancy Loss

Quick Facts

Study Start:2021-09-01
Study Completion:2026-09
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05444283

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 50 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Yong-Hui Jiang, MD, PhD
CONTACT
2037852429
yong-hui.jiang@yale.edu
Heping Zhang, PhD
CONTACT
12037855185
heping.zhang@yale.edu

Study Locations (Sites)

University of Colorado
Aurora, Colorado, 80045
United States
Yale University
New Haven, Connecticut, 06511
United States
Northwestern University
Chicago, Illinois, 60611
United States
University of Chicago
Chicago, Illinois, 60611
United States
Gaelle Massoud
Baltimore, Maryland, 21205
United States
Wayne State University
Detroit, Michigan, 48201
United States
Columbia University
New York, New York, 10032
United States
University of Oklahoma
Oklahoma City, Oklahoma, 73104
United States
Pennsylvania State University
Hershey, Pennsylvania, 17033
United States
University of Texas at Austin
Austin, Texas, 78712
United States
University of Texas at San Antonio
San Antonio, Texas, 78299
United States

Collaborators and Investigators

Sponsor: Yale University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-09-01
Study Completion Date2026-09

Study Record Updates

Study Start Date2021-09-01
Study Completion Date2026-09

Terms related to this study

Additional Relevant MeSH Terms

  • Recurrent Pregnancy Loss