RECRUITING

Brain Health With Inner Engineering Meditation

Conditions

Meditation Brain; Agenesis Functional MRI EEG Structural MRI Shambhavi Mahamudra Kriya Mindfulness

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This study will explore whether a 21-minute meditation practice called Shambhavi Mahamudra Kriya leads to changes in brain health and explore how it affects cognitive and physiological function.

Official Title

Brain Health With Inner Engineering- Longitudinal Study of Shambhavi Mahamudra Kriya Meditation (BLISS)

Quick Facts

Study Start:2023-01-06

Study Completion:2024-12

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05455814

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:20 Years to 65 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Individuals between the ages of 20-65 years. * Subjects will be required to be able to understand study instructions and provide informed consent. * Currently residing in Massachusetts.	* Non-English Speaking. (Justification: Meditation and cognitive assessment instruments are not validated in a sufficient range of languages, and the research team lacks polylingual capabilities or the financial resources to hire interpreters for the duration of all proposed assessments.) * Practicing meditation regularly for the past 6 months (3 or more times per week of practice regularly for the past 6 month). * History of psychiatric illness such as severe anxiety, severe depression, Schizophrenia or bipolar disorder. * History of any form of cognitive decline or neurological conditions such as dementia, Parkinson's disease, Alzheimer's disease, Huntington's disease, brain tumors, brain surgery. * Current use of cognition enhancing drugs * Current management for chronic pain. * History (within the last 5 years) of stroke/aneurysm. * Active history (within the last 5 years) of alcohol or drug abuse (\> 10 drinks per week). * Current pregnancy or planning to become pregnant in the next 6 months. * Currently enrolled in another interventional study that could impact the primary outcome, as determined by the PI. * Educational attainment below high school level or equivalent. * Significant visual impairment.

Inclusion Criteria

Exclusion Criteria

* Individuals between the ages of 20-65 years.
* Subjects will be required to be able to understand study instructions and provide informed consent.
* Currently residing in Massachusetts.

* Non-English Speaking. (Justification: Meditation and cognitive assessment instruments are not validated in a sufficient range of languages, and the research team lacks polylingual capabilities or the financial resources to hire interpreters for the duration of all proposed assessments.)
* Practicing meditation regularly for the past 6 months (3 or more times per week of practice regularly for the past 6 month).
* History of psychiatric illness such as severe anxiety, severe depression, Schizophrenia or bipolar disorder.
* History of any form of cognitive decline or neurological conditions such as dementia, Parkinson's disease, Alzheimer's disease, Huntington's disease, brain tumors, brain surgery.
* Current use of cognition enhancing drugs
* Current management for chronic pain.
* History (within the last 5 years) of stroke/aneurysm.
* Active history (within the last 5 years) of alcohol or drug abuse (\> 10 drinks per week).
* Current pregnancy or planning to become pregnant in the next 6 months.
* Currently enrolled in another interventional study that could impact the primary outcome, as determined by the PI.
* Educational attainment below high school level or equivalent.
* Significant visual impairment.

Contacts and Locations

Study Contact

Balachundar Subramaniam, MD, MPH

CONTACT

617-667-2721

sadhgurucenter_research@bidmc.harvard.edu

Sepideh Hariri, MD, MPH

CONTACT

sadhgurucenter_research@bidmc.harvard.edu

Principal Investigator

Balachundar Subramaniam, MD, MPH

PRINCIPAL_INVESTIGATOR

Beth Israel Deaconess Medical Center

Study Locations (Sites)

Beth Israel Deaconess Medical Centre

Boston, Massachusetts, 02115

United States

Collaborators and Investigators

Sponsor: Beth Israel Deaconess Medical Center

Balachundar Subramaniam, MD, MPH, PRINCIPAL_INVESTIGATOR, Beth Israel Deaconess Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-06

Study Completion Date2024-12

Study Record Updates

Study Start Date2023-01-06

Study Completion Date2024-12

Terms related to this study

Keywords Provided by Researchers

Functional MRI
EEG
Structural MRI
Shambhavi Mahamudra Kriya
Mindfulness

Additional Relevant MeSH Terms

Meditation
Brain; Agenesis