RECRUITING

CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Depression in youth is a serious public health concern for which more personalized treatments are needed. This randomized controlled trial will test the effect of an intervention aimed at enhancing social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in the R33 (N=82) will be youth between ages 13- through 17-years-old currently experiencing depression. Youth will be randomized to either an enhanced CBT intervention that teaches social cognitive skills, particularly social perspective taking and theory of mind (CBTSCT) as compared to CBT only. The primary target is improvement in both social cognitive skills and depressive symptoms at post-treatment and at a 6-month follow-up.

Official Title

Social Cognitive Training to Enhance the Efficacy of CBT forDepression in Youth: A Developmental Approach (R33)

Quick Facts

Study Start:2022-10-10
Study Completion:2026-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05456035

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:13 Years to 17 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. 1. Participants ages 13- through 17-years-old
  2. 2. Youth must have a diagnosis of a current depressive disorder (e.g., major depressive episode; persistent depressive disorder) or a score on the Patient Health Questionnaire (PHQ9) \> 15
  1. * ever met criteria for a diagnosis of bipolar disorder, schizophrenia, autism, or conduct disorder
  2. * current alcohol or substance use disorder with significant impairment
  3. * imminent risk of suicide
  4. * reading level \< 4th grade

Contacts and Locations

Study Contact

Judy Garber, PhD
CONTACT
615-330-5605
judy.garber@vanderbilt.edu
Steven D Hollon, PhD
CONTACT
615-373-2422
steven.d.hollon@vanderbilt.edu

Study Locations (Sites)

Judy Garber
Nashville, Tennessee, 37203-5721
United States

Collaborators and Investigators

Sponsor: Vanderbilt University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-10-10
Study Completion Date2026-02

Study Record Updates

Study Start Date2022-10-10
Study Completion Date2026-02

Terms related to this study

Keywords Provided by Researchers

  • Depression
  • Adolescents
  • Cognitive behavior therapy

Additional Relevant MeSH Terms

  • Depression