Digital CBT for Insomnia and Depression

Description

This study has two primary objectives, each of which addresses critical clinical and research gaps for individuals who have co-occurring insomnia and depression. The first objective is to address whether sequential treatment of insomnia and depression is superior to a single treatment for either depression or for insomnia, and if so, which treatment sequence is optimal. The second objective is to determine if there are heterogeneity of treatment effects; that is, variation in which interventions are best for which individuals, and if so, to develop and individualized intervention rule to better match individuals with the treatment that is most likely to lead to the best outcomes. A large randomized trial will be conducted to meet these objectives.

Conditions

Depression, Insomnia

Study Overview

Study Details

Study overview

This study has two primary objectives, each of which addresses critical clinical and research gaps for individuals who have co-occurring insomnia and depression. The first objective is to address whether sequential treatment of insomnia and depression is superior to a single treatment for either depression or for insomnia, and if so, which treatment sequence is optimal. The second objective is to determine if there are heterogeneity of treatment effects; that is, variation in which interventions are best for which individuals, and if so, to develop and individualized intervention rule to better match individuals with the treatment that is most likely to lead to the best outcomes. A large randomized trial will be conducted to meet these objectives.

Optimizing Digital Behavioral Treatment for Co-occurring Insomnia and Depression

Digital CBT for Insomnia and Depression

Condition
Depression
Intervention / Treatment

-

Contacts and Locations

Rochester

University of Rochester Sleep Research Laboratory, Rochester, New York, United States, 14642

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * English-speaking
  • * U.S. Military Veterans
  • * endorse depression (Patient Health Questionnaire-depression score \> 10)
  • * endorse insomnia (Insomnia Severity Index score \> 10).
  • * pregnancy
  • * history of bipolar disorder
  • * history of psychosis
  • * current use of anti-psychotic medications or mood stabilizers (e.g., lithium)
  • * current suicidal ideation with active intent

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Rochester,

Wilfred Pigeon, PhD, PRINCIPAL_INVESTIGATOR, University of Rochester

Study Record Dates

2027-09-30