RECRUITING

Multiomic Diagnostics in Youth With Psychosis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Rady Children's Institute for Genomic Medicine seeks to understand the genomes and immune systems in 15 children and adolescents who are admitted to Rady Children's Hospital Child and Adolescent Psychiatry Service with psychotic symptoms or schizophrenia. Cutting-edge genome and protein sequencing technology will be used to better understand how immunological and genetic assessments may improve our ability to identify the cause of psychosis and impact care. The investigator also hopes to identify new genetic and/or autoimmune causes of psychosis that may inform new treatment for future patients.

Official Title

Multiomic Diagnostics in Child and Adolescent Psychosis

Quick Facts

Study Start:2022-10-10
Study Completion:2026-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05457140

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:7 Years to 17 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. 1. Child/adolescent admitted to the Rady Children's CAPS with symptoms of first break psychosis
  2. 2. Biological parents of child/adolescent enrolled in this study for the purposes of reflex testing. Family members are eligible for participation in this study if they are presumed genetically related to a patient participant.
  1. 1. Already received any prior whole genome sequencing or exome sequencing.
  2. 2. Unable to approach the family or patient for enrollment.
  3. 3. Unable to obtain informed consent.
  4. 4. Family members are ineligible for participation in this study if:
  5. 1. They are known to not be genetically related to the child/adolescent patient participant
  6. 2. They are a member of a protected research population

Contacts and Locations

Study Contact

Aaron Besterman, MD
CONTACT
858-576-1700
abesterman@health.ucsd.edu
Corrine Blucher, BS
CONTACT
858-576-1700
cblucher@rchsd.org

Principal Investigator

Aaron Besterman, MD
PRINCIPAL_INVESTIGATOR
Rady Pediatric Genomics & Systems Medicine Institute

Study Locations (Sites)

Rady Children's Hospital San Diego
San Diego, California, 92123
United States

Collaborators and Investigators

Sponsor: Rady Pediatric Genomics & Systems Medicine Institute

  • Aaron Besterman, MD, PRINCIPAL_INVESTIGATOR, Rady Pediatric Genomics & Systems Medicine Institute

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-10-10
Study Completion Date2026-08

Study Record Updates

Study Start Date2022-10-10
Study Completion Date2026-08

Terms related to this study

Keywords Provided by Researchers

  • Genomic
  • Pediatric
  • Rady Children's Hospital

Additional Relevant MeSH Terms

  • Psychosis