Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * Not weight stable (\<5% change in body mass over the past six months)
- * Overt cardiovascular, neurological, renal, liver, and/or metabolic illness (e.g., diabetes mellitus)
- * Current, or history of uncontrolled, Stage 2 hypertension (blood pressure \>140 / 90 mmHg; anti-hypertensive medications are permitted)
- * Diagnosed obstructive sleep apnea
- * Previous bariatric surgery
- * Diagnosis or signs (e.g., values below the lower limit of normal) of overt airway disease(s)
- * Current or recent (regular use within the past 6 months) use of tobacco or nicotine products (e.g., cigarettes, vaping)
- * Pregnant (self-reported and confirmed via urine pregnancy test), lactating (self-reported), or post-menopausal (self-reported) females
- * Prisoners
- * Per the POWERbreathe® company:
- * Patients who have undergone recent abdominal surgery and those with abdominal hernia.
- * Asthma patients who have a very low symptom perception and suffer from frequent, severe exacerbations or with an abnormally low perception of dyspnea.
- * If a patient is suffering from a ruptured eardrum or any other condition of the ear.
- * Patients with marked elevated left ventricular end-diastolic volume and pressure.
- * Patients with worsening heart failure signs and symptoms after training.
- * If an individual is suffering from a cold, sinusitis or respiratory tract infection, it is advised that they do not use the POWERbreathe device.
Ages Eligible for Study
20 Years to 45 Years
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
Yes