ACTIVE_NOT_RECRUITING

Clinical Trial of Molecular Biomarkers in Women With Uterine Cervix Cancer

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a phase 0 clinical trial of molecular biomarkers in women with uterine cervix cancer. Women receive standard-of-care radiochemotherapy followed by brachytherapy. Blood samples are obtained to detect circulating levels of deoxyribonucleotides, human papillomavirus DNA, and circulating tumor cells.

Official Title

Phase 0 Clinical Trial of Molecular Biomarkers in Women With Uterine Cervix Cancer

Quick Facts

Study Start:2023-01-03

Study Completion:2026-06-01

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:ACTIVE_NOT_RECRUITING

Study ID

NCT05462951

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:FEMALE

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
Age 18 years or older Willing and able to provide informed consent Able to understand and follow study procedures Stable medical condition	* Presence of another concurrent active invasive malignancy * Prior invasive malignancy diagnosed within the last three years except for \[1\] non-melanoma skin cancer or \[2\] prior in situ carcinoma of the cervix * prior pelvic radiotherapy for any reason that would contribute radiation dose that would exceed tolerance of normal tissues at the discretion of the treating physician.

Contacts and Locations

Principal Investigator

Denise Fabian, MD

PRINCIPAL_INVESTIGATOR

University of Kentucky

Study Locations (Sites)

Markey Cancer Center

Lexington, Kentucky, 40536

United States

Collaborators and Investigators

Sponsor: Denise Fabian

Denise Fabian, MD, PRINCIPAL_INVESTIGATOR, University of Kentucky

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-03

Study Completion Date2026-06-01

Study Record Updates

Study Start Date2023-01-03

Study Completion Date2026-06-01

Terms related to this study

Additional Relevant MeSH Terms

Uterine Cervix Cancer