RECRUITING

SV2A in Older Adults

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The aim of the study is to examine the effect of cannabis use on brain synaptic density among older adults using \[11C\]UCB-J PET imaging.

Official Title

Effect of Cannabis Use on Synaptic Density in Older Adults

Quick Facts

Study Start:2022-07-06

Study Completion:2025-09-30

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05465538

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:50 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Able to provide informed consent * Male or female, aged ≥50 years * No history of significant medical or neurological disease * BMI ≤ 50 * If woman of childbearing potential, must agree to use an acceptable method of birth control, as determined by the principal investigator, for the duration of the study and up to one month after completion of PET scans	* Women with a positive pregnancy test or women who are lactating * Have had exposure to ionizing radiation that in combination with the study tracer would result in a cumulative exposure that exceeds recommended exposure limits; * History of a bleeding disorder or are currently taking anticoagulants * Subjects who have donated blood within 8 weeks of the present study

Contacts and Locations

Study Contact

Rajiv Radhakrishnan, MBBS, MD

CONTACT

203-932-5711

rajiv.radhakrishnan@yale.edu

Principal Investigator

Rajiv Radhakrishnan, MBBS, MD

PRINCIPAL_INVESTIGATOR

Yale University

Study Locations (Sites)

Connecticut Mental Health Center

New Haven, Connecticut, 06519

United States

Collaborators and Investigators

Sponsor: Yale University

Rajiv Radhakrishnan, MBBS, MD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-07-06

Study Completion Date2025-09-30

Study Record Updates

Study Start Date2022-07-06

Study Completion Date2025-09-30

Terms related to this study

Additional Relevant MeSH Terms

Cannabis Use