RECRUITING

The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to determine if an acute bout of removal of exercise reduces enothelial function and glycemic control in an active, older adult population; and whether a 3 day return to exercise restores this response. Glycemic control is the blood glucose response following the consumption of a meal. It is an indicator of insulin resistance (or type 2 diabetes) and impaired glycemic control has been suggested to lead to cardiovascular disease. Endothelial function has been shown to be improved by chronic or acute increases in physical activity. Both of these have been shown to be impaired to acute bouts of inactivity in young populations; however the impact of acute inactivity in older adults is less understood. In this proposal the investigators will examine 1)how quickly impairments in glycemic control occur to acute physical inactivity in older adults who exercise, 2) how quickly impairments in endothelial function occur to acute inactivity in older adults who exercise, and 3) whether 3 days of a return to exercise restores these responses.

Official Title

The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active

Quick Facts

Study Start:2022-07-25
Study Completion:2025-04-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05468255

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. 55 years and older, 18-40 years old
  2. 2. Healthy, physically active, performing at least 90 min/week of physical activity
  3. 3. Free of physical limitations that may interfere with alterations in daily physical activity levels
  1. 1. Physician diagnosed HIV, hepatitis, or tuberculosis.
  2. 2. Body weight change of greater than 5% within the previous 2 months
  3. 3. Smoking within the previous 2 months.
  4. 4. Taking medications that alter blood glucose levels

Contacts and Locations

Study Contact

Leryn Reynolds
CONTACT
757-683-4974
lreynold@odu.edu

Study Locations (Sites)

Old Dominion University
Norfolk, Virginia, 23529
United States

Collaborators and Investigators

Sponsor: Old Dominion University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-07-25
Study Completion Date2025-04-01

Study Record Updates

Study Start Date2022-07-25
Study Completion Date2025-04-01

Terms related to this study

Additional Relevant MeSH Terms

  • Glucose Intolerance
  • Exercise
  • Vascular Function