Comparing Perclose to Statseal in Conjunction with Perclose in Femoral 6 French Arteriotomy Closure

Eligibility Criteria

• * Patient undergoing diagnostic angiography or PCI with femoral access who undergo PercloseTM closure.
• * Catheterization with a 6Fr system
• * Those with a planned radial approach will also be enrolled given the possibility of changing to femoral access in the catheterization lab if radial access is not possible given radial artery spasm, significant patient discomfort with a contraindication to greater levels of sedation, inability to transverse guidewire into the aortic root, inability to engage coronary artery or deliver equipment, or other clinically indicated reason.
• * Use of a hemostasis method or device besides PercloseTM (Perclose may not be used in situations of heavy calcification, presence of dissection, etc).
• * Patients undergoing catheterization only from the radial, brachial, ulnar, or distal radial (snuffbox) artery approach.
• * Use of an anticoagulant other than unfractionated heparin or bivalirudin.
• * Any use of glycoprotein inhibitors or cangrelor.
• * Use of sheathless guides.
• * Any anticipated need for continued anticoagulation post-catheterization, including extended bivalirudin infusion.
• * Any active treatment with oral anticoagulants continued during course of procedure.
• * Presence of arteriovenous dialysis fistula in the ipsilateral leg.
• * Any physical deformity or trauma / injury of the leg that would prevent proper placement or function of the hemostasis band.
• * Inability of the patient to personally consent for the study. (no surrogate consent)
• * Cardiogenic shock, emergent procedures (high risk myocardial infarctions), or any clinical instability as assessed by the physician performing the procedure.