RECRUITING

COVID-19 Outcome Prediction Algorithm

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hospitalized civilian population in one of the country's largest metropolitan areas and a representative National Veteran's population.

Official Title

Multi-Dimensional Outcome Prediction Algorithm for Hospitalized COVID-19 Patients

Quick Facts

Study Start:2022-08-08
Study Completion:2026-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05471011

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Symptomatic COVID-19 infection with hospital admission
  2. * Age 18 and above
  3. * Informed consent
  1. * Absence of symptomatic COVID-19 infection with hospital admission
  2. * Age 17 or below
  3. * No informed consent

Contacts and Locations

Study Contact

Mario C Deng, MD
CONTACT
3107532759
mdeng@mednet.ucla.edu
David Beenhouwer, MD
CONTACT
3104783711
dbeenhou@g.ucla.edu

Study Locations (Sites)

VA Greater Los Angeles Healthcare System
Los Angeles, California, 90073
United States
Ronald Reagan UCLA Medical Center
Los Angeles, California, 90095
United States
Olive View-UCLA Education & Research Institute
Sylmar, California, 91342
United States
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Torrance, California, 90502
United States
Atlanta VA Medical Center
Decatur, Georgia, 30033
United States
Bronx VA Medical Center
Bronx, New York, 10468
United States
Michael E. DeBakey VA Medical Center
Houston, Texas, 77030
United States

Collaborators and Investigators

Sponsor: University of California, Los Angeles

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-08-08
Study Completion Date2026-05-31

Study Record Updates

Study Start Date2022-08-08
Study Completion Date2026-05-31

Terms related to this study

Keywords Provided by Researchers

  • outcome prediction
  • systems biology
  • multiomics
  • algorithm
  • veterans
  • high-risk populations

Additional Relevant MeSH Terms

  • COVID-19
  • Post Acute Sequelae of COVID-19
  • Long COVID
  • Organ Dysfunction Syndrome, Multiple
  • Frailty Syndrome