COVID-19 Outcome Prediction Algorithm

Description

Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hospitalized civilian population in one of the country's largest metropolitan areas and a representative National Veteran's population.

Conditions

COVID-19, Post Acute Sequelae of COVID-19, Long COVID, Organ Dysfunction Syndrome, Multiple, Frailty Syndrome

Study Overview

Study Details

Study overview

Severe acute respiratory syndrome coronavirus 2-mediated coronavirus disease (COVID-19) is an evolutionarily unprecedented natural experiment that causes major changes to the host immune system. We propose to develop a test that accurately predicts short- and long-term (within one-year) outcomes in hospitalized COVID-19 patients broadly reflecting US demographics who are at increased risk of adverse outcomes from COVID-19 using both clinical and molecular data. We will enroll patients from a hospitalized civilian population in one of the country's largest metropolitan areas and a representative National Veteran's population.

Multi-Dimensional Outcome Prediction Algorithm for Hospitalized COVID-19 Patients

COVID-19 Outcome Prediction Algorithm

Condition
COVID-19
Intervention / Treatment

-

Contacts and Locations

Los Angeles

VA Greater Los Angeles Healthcare System, Los Angeles, California, United States, 90073

Los Angeles

Ronald Reagan UCLA Medical Center, Los Angeles, California, United States, 90095

Sylmar

Olive View-UCLA Education & Research Institute, Sylmar, California, United States, 91342

Torrance

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States, 90502

Decatur

Atlanta VA Medical Center, Decatur, Georgia, United States, 30033

Bronx

Bronx VA Medical Center, Bronx, New York, United States, 10468

Houston

Michael E. DeBakey VA Medical Center, Houston, Texas, United States, 77030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Symptomatic COVID-19 infection with hospital admission
  • * Age 18 and above
  • * Informed consent
  • * Absence of symptomatic COVID-19 infection with hospital admission
  • * Age 17 or below
  • * No informed consent

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of California, Los Angeles,

Study Record Dates

2026-05-31