RECRUITING

Estimating Risk of Respiratory Infections Attributable to CFTR Heterozygosity

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

A research team member will brush the inferior surface of the subjects' middle turbinate (nasal cavity) using a cytology brush to obtain the cells needed to perform our functional respiratory assays. An individual trained in phlebotomy will draw one 3 ml lavender top tube of blood to test c-reactive protein, calprotectin, and lactoferrin. They will also draw a 5 ml gold top serum separator tube of blood to test fibroblast growth factor-19. The participant will answer questions from the baseline survey and report their current medications interview-style with the research team member.

Official Title

Estimating the Risk for and Severity of Respiratory Infections Attributable to CFTR Heterozygosity

Quick Facts

Study Start:2021-12-20
Study Completion:2024-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05474430

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 100 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Previously tested and shown to be a CF carrier
  2. * English-speaking
  1. * Currently sick with a respiratory infection
  2. * Prisoner Status
  3. * Unable to provide own written, informed consent

Contacts and Locations

Study Contact

Philip M Polgreen, MD
CONTACT
(319) 384-6194
philip-polgreen@uiowa.edu
Shelby L Francis, PhD
CONTACT
319-678-8037
shelby-francis@uiowa.edu

Principal Investigator

Philip M Polgreen, MD
PRINCIPAL_INVESTIGATOR
University of Iowa

Study Locations (Sites)

University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242
United States

Collaborators and Investigators

Sponsor: Philip Polgreen

  • Philip M Polgreen, MD, PRINCIPAL_INVESTIGATOR, University of Iowa

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-12-20
Study Completion Date2024-07

Study Record Updates

Study Start Date2021-12-20
Study Completion Date2024-07

Terms related to this study

Additional Relevant MeSH Terms

  • Carrier State
  • Respiratory Infections