Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft

Description

The primary aims of this study are to compare, after 4 months, the clinical and histologic results of a combination demineralized/mineralized putty allograft vs. synthetic calcium phosphosilicate (CPS) putty alloplast graft utilization in socket preservation procedures. A regenerative tissue matrix membrane will be used to cover each graft lying below the flap.

Conditions

Alveolar Bone Resorption

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Study Overview

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Study Details

Study overview

The primary aims of this study are to compare, after 4 months, the clinical and histologic results of a combination demineralized/mineralized putty allograft vs. synthetic calcium phosphosilicate (CPS) putty alloplast graft utilization in socket preservation procedures. A regenerative tissue matrix membrane will be used to cover each graft lying below the flap.

Ridge Preservation Comparing the Clinical and Histologic Healing of Two Different Putty Bone Grafts

Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft

Condition
Alveolar Bone Resorption
Intervention / Treatment

-

Contacts and Locations

Louisville

University of Louisville, Louisville, Kentucky, United States, 40202

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Have one non-molar tooth requiring extraction that will be replaced by a dental implant.
  • 2. Healthy male or female who is at least 18 years old.
  • 3. Patients must sign an informed consent approved by the University of Louisville Human Studies Committee.
  • 1. Patients with debilitating systemic diseases, or diseases that have a clinically significant effect on the periodontium.
  • 2. Presence or history of osteonecrosis of jaws.
  • 3. Patients who are currently taking IV bisphosphonates or who had IV treatment with bisphosphonates irrespective of duration.
  • 4. Patients who have been treated with oral bisphosphonates for more than three years.
  • 5. Patients with an allergy to any material or medication used in the study.
  • 6. Patients who need prophylactic antibiotics
  • 7. Previous head and neck radiation therapy.
  • 8. Chemotherapy in the previous 12 months.
  • 9. Patients on long term NSAID or steroid therapy.
  • 10. Pregnant patients.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Louisville,

Bindu Dukka, BDS,MSD,MPH, PRINCIPAL_INVESTIGATOR, Director, Graduate Periodontics, University of Louisville

Study Record Dates

2024-10-30