A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Description

This registry evaluates patient characteristics, real-world treatment patterns, and short- and long-term outcomes in a population of patients in the United States and Europe with symptomatic obstructive hypertrophic cardiomyopathy (HCM) who are receiving mavacamten, receiving other treatment for obstructive HCM, or not receiving treatment for obstructive HCM due to intolerance or failure of prior treatment. United States Sub-Study: The purpose of this study is to evaluate the safety of mavacamten in patients with symptomatic obstructive HCM in the real-world setting. Europe Sub-Study: The purpose of this study is to evaluate the effectiveness and safety of mavacamten in patients with symptomatic obstructive HCM in the real-world setting.

Conditions

Obstructive Hypertrophic Cardiomyopathy

Study Overview

Study Details

Study overview

This registry evaluates patient characteristics, real-world treatment patterns, and short- and long-term outcomes in a population of patients in the United States and Europe with symptomatic obstructive hypertrophic cardiomyopathy (HCM) who are receiving mavacamten, receiving other treatment for obstructive HCM, or not receiving treatment for obstructive HCM due to intolerance or failure of prior treatment. United States Sub-Study: The purpose of this study is to evaluate the safety of mavacamten in patients with symptomatic obstructive HCM in the real-world setting. Europe Sub-Study: The purpose of this study is to evaluate the effectiveness and safety of mavacamten in patients with symptomatic obstructive HCM in the real-world setting.

Deliver Insights in Hypertrophic Cardiomyopathy and Observational Outcomes in Real World: United States and European Prospective Registry Study

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Condition
Obstructive Hypertrophic Cardiomyopathy
Intervention / Treatment

-

Contacts and Locations

Anchorage

Alaska Heart Institute, Anchorage, Alaska, United States, 99508

Tucson

Pima Heart and Vascular, Tucson, Arizona, United States, 85704

Little Rock

UAMS, Little Rock, Arkansas, United States, 72205-7199

La Jolla

UC San Diego School of Medicine, La Jolla, California, United States, 92037

Los Angeles

Keck School of Medicine of USC-Usc, Los Angeles, California, United States, 90033

Palo Alto

Stanford Health Care Hospital & Clinics, Palo Alto, California, United States, 94304

San Francisco

University Of California San Francisco Medical Center, San Francisco, California, United States, 94117

Aurora

UC Denver, AMC, Aurora, Colorado, United States, 48377

Hartford

Hartford HealthCare, Hartford, Connecticut, United States, 06106

Washington

MedStar Washington Hospital Center, Washington, District of Columbia, United States, 20010

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Bristol-Myers Squibb,

    Bristol-Myers Squibb, STUDY_DIRECTOR, Bristol-Myers Squibb

    Study Record Dates

    2029-08-15