RECRUITING

The Heartland Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S.. The objective of the Heartland Study is to address major knowledge gaps concerning the health effects of herbicides on maternal and infant health. The study is being conducted to evaluate the associations between environmental exposures to herbicides during and after pregnancy and reproductive health outcomes. The study is measuring multiple biomarkers of herbicide exposure among pregnant Midwesterners and their partners to evaluate associations with pregnancy and childbirth outcomes, epigenetic biomarkers of exposure, and child development.

Official Title

Children's Health in the Heartland Study

Quick Facts

Study Start:2020-01-11
Study Completion:2029-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05492708

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Pregnant persons ages 18 or older at time of consent who are ≤20+6 weeks pregnant. Best clinical estimate of gestational age will be utilized for recruitment purposes. Enrollment in the first trimester (≤ 13 + 6) is preferred, but anyone ≤ 20 +6 is permitted.
  2. * Living in one of the 13 Heartland Study region states at the time of enrollment (Arkansas, Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, or Wisconsin) Optional inclusion of the putative biological father
  1. * Participants who are not fluent in and/or do not fully understand, read, write, or speak the English language.
  2. * Other inability to provide informed consent to participate

Contacts and Locations

Study Contact

Kathleen Flannery
CONTACT
317-880-3961
kamaflan@iu.edu

Study Locations (Sites)

Indiana University Medical Center
Indianapolis, Indiana, 46202
United States
University of Iowa Health Care
Iowa City, Iowa, 52242
United States
Gundersen Health
La Crosse, Wisconsin, 54601
United States
Marshfield Clinic
Marshfield, Wisconsin, 54449
United States

Collaborators and Investigators

Sponsor: Heartland Health Research Alliance

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-01-11
Study Completion Date2029-01

Study Record Updates

Study Start Date2020-01-11
Study Completion Date2029-01

Terms related to this study

Keywords Provided by Researchers

  • pesticide exposure
  • birth outcomes
  • biomonitoring

Additional Relevant MeSH Terms

  • Pregnancy Related
  • Pregnancy Complications
  • Birth Defect
  • Gestational Age and Weight Conditions
  • Spontaneous Abortion
  • Miscarriage
  • Exposure to Herbicides