Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

Description

Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.

Conditions

Refractory Epilepsy, Deep Brain Stimulation

Study Overview

Study Details

Study overview

Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.

Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

Condition
Refractory Epilepsy
Intervention / Treatment

-

Contacts and Locations

Minneapolis

University of Minnesota, Minneapolis, Minnesota, United States, 55455

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * medically refractory epilepsy
  • * already have a deep brain stimulator in place
  • * severe dementia at investigator discretion

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Minnesota,

Robert McGovern, MD, PRINCIPAL_INVESTIGATOR, University of Minnesota

Study Record Dates

2030-01-15