RECRUITING

Exercise Reset for Concussion in a Military Environment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Our primary objective is to show that early, personalized aerobic exercise treatment safely improves concussion recovery, speeds RTD, and reduces persistent symptoms in CSM. Our secondary objectives include demonstrating the clinical utility of our March-in-place test and determining fundamental mechanisms for the effect of exercise rehabilitation on concussion recovery.

Official Title

Exercise Reset for Concussion- Modifying the Buffalo Concussion Protocol for Application in a Military Environment

Quick Facts

Study Start:2024-08-07
Study Completion:2026-03-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05498038

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 40 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Aged 18-40 years,
  2. * Within 9 days of injury
  3. * Diagnosed with concussion by an experienced clinician using standard international criteria
  1. * Moderate or severe TBI as indicated by a GCS score \<13, lesion on CT/MRI, and/or focal neurologic sign consistent with intracerebral lesion
  2. * Injury involving loss of consciousness for \>30 minutes or post-traumatic amnesia \>24 hours
  3. * Inability to exercise because of lower-extremity orthopedic injury, clinically significant vestibular or visual dysfunction, or increased cardiac risk
  4. * Pre-existing conditions that prevent participation in active testing and/or rehabilitation
  5. * History of more than 3 diagnosed concussions
  6. * Currently on medications that affect autonomic function, such as ADHD medication or mood stabilizers
  7. * Active substance abuse/dependence
  8. * Unwillingness to perform intervention
  9. * Limited English proficiency.

Contacts and Locations

Study Contact

John J Leddy, MD
CONTACT
716-829-5499
leddy@buffalo.edu
Haley Chizuk, PhD, ATC
CONTACT
7162043200
haleychi@buffalo.edu

Principal Investigator

John Leddy, MD
PRINCIPAL_INVESTIGATOR
University at Buffalo

Study Locations (Sites)

Fort Liberty
Fayetteville, North Carolina, 28310
United States
Camp LeJeune
Jacksonville, North Carolina, 28547
United States

Collaborators and Investigators

Sponsor: State University of New York at Buffalo

  • John Leddy, MD, PRINCIPAL_INVESTIGATOR, University at Buffalo

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-08-07
Study Completion Date2026-03-01

Study Record Updates

Study Start Date2024-08-07
Study Completion Date2026-03-01

Terms related to this study

Keywords Provided by Researchers

  • aerobic exercise
  • military
  • service member*
  • concussion management

Additional Relevant MeSH Terms

  • Brain Concussion