An Examination of Brown Adipose Tissue and Energy Expenditure in Infants

Description

Excess fetal adipose tissue growth during intrauterine development increases future obesity risk. Development of brown adipose tissue, a highly thermogenic organ in utero, may affect postnatal energy expenditure, thus influencing obesity risk. This research study is designed to understand the developmental origins of energy balance by examining maternal and neonatal factors that influence neonatal brown adipose tissue and to quantify its physiological relevance to energy expenditure in human neonates.

Conditions

Brown Adipose Tissue

Study Overview

Study Details

Study overview

Excess fetal adipose tissue growth during intrauterine development increases future obesity risk. Development of brown adipose tissue, a highly thermogenic organ in utero, may affect postnatal energy expenditure, thus influencing obesity risk. This research study is designed to understand the developmental origins of energy balance by examining maternal and neonatal factors that influence neonatal brown adipose tissue and to quantify its physiological relevance to energy expenditure in human neonates.

An Examination of Brown Adipose Tissue and Energy Expenditure in Infants

An Examination of Brown Adipose Tissue and Energy Expenditure in Infants

Condition
Brown Adipose Tissue
Intervention / Treatment

-

Contacts and Locations

Baton Rouge

Pennington Biomedical Research Center, Baton Rouge, Louisiana, United States, 70808

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * aged 0 weeks to less than 3 weeks at visit 1
  • * be willing to complete MRI procedures
  • * Unable to complete two clinic visits within 14 days
  • * Born with health conditions that would render the procedures unsafe
  • * Born earlier than 36 and 0 days gestation
  • * Taken a steroid drug since birth
  • * Implanted metal or electronic objects that render MRI unsafe

Ages Eligible for Study

to 5 Weeks

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Pennington Biomedical Research Center,

Emily W Flanagan, PhD, PRINCIPAL_INVESTIGATOR, Pennington Biomedical Research Center

Study Record Dates

2025-12-31