RECRUITING

An Examination of Brown Adipose Tissue and Energy Expenditure in Infants

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Excess fetal adipose tissue growth during intrauterine development increases future obesity risk. Development of brown adipose tissue, a highly thermogenic organ in utero, may affect postnatal energy expenditure, thus influencing obesity risk. This pilot research study is designed to understand the developmental origins of energy balance by examining maternal and neonatal factors that influence neonatal brown adipose tissue and to quantify its physiological relevance to energy expenditure in human neonates.

Official Title

An Examination of Brown Adipose Tissue and Energy Expenditure in Infants

Quick Facts

Study Start:2022-08-17
Study Completion:2025-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05517967

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 5 Weeks
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * aged 0 weeks to less than 3 weeks at visit 1
  2. * be willing to complete MRI procedures
  1. * Unable to complete two clinic visits within 14 days
  2. * Born with health conditions that would render the procedures unsafe
  3. * Born earlier than 36 and 0 days gestation
  4. * Taken a steroid drug since birth
  5. * Implanted metal or electronic objects that render MRI unsafe

Contacts and Locations

Study Contact

Emily W Flanagan, PhD
CONTACT
225-763-2828
emily.flanagan@pbrc.edu
Abby D Altazan, MS
CONTACT
225-763-2801
abby.duhe@pbrc.edu

Principal Investigator

Emily W Flanagan, PhD
PRINCIPAL_INVESTIGATOR
Pennington Biomedical Research Center

Study Locations (Sites)

Pennington Biomedical Research Center
Baton Rouge, Louisiana, 70808
United States

Collaborators and Investigators

Sponsor: Pennington Biomedical Research Center

  • Emily W Flanagan, PhD, PRINCIPAL_INVESTIGATOR, Pennington Biomedical Research Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-08-17
Study Completion Date2025-12-31

Study Record Updates

Study Start Date2022-08-17
Study Completion Date2025-12-31

Terms related to this study

Keywords Provided by Researchers

  • Infant
  • Energy Expenditure
  • Indirect Calorimetry
  • Brown Fat
  • Neonatal
  • Magnetic Resonance Imaging

Additional Relevant MeSH Terms

  • Cold Induced Thermogenesis