@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms

Description

The primary aim of the SwissNeuroFoundation AneurysmDataBase Project is to implement information technology based tools to create and use a holistic reference database specific to intracranial aneurysms (IA). The SwissNeuroFoundation AneurysmDataBase are concerned with generating the data with which to populate this database. The purpose for populating the database are to: * Screen for and evaluate markers of risk for intracranial aneurysm formation and aneurysm rupture. Are considered as markers the following: genetics factors, microbiota, environmental factors, congenital factors (ie: cerebrovascular anatomical variants), transcriptomics signature, proteomics signature,shape characteristics, haemodynamics characteristics. * Screen for and evaluate prognostic factors of outcome regarding different management strategies including watchful observation, microsurgical treatment, endovascular treatment or any combination thereof. * Implement and evaluate patient-specific management protocols integrating all available information. * Evaluate the impact of the database and use of tools to improve care, reduce costs, support knowledge discovery and promote new industrial developments.

Conditions

Intracranial Aneurysm

Study Overview

Study Details

Study overview

The primary aim of the SwissNeuroFoundation AneurysmDataBase Project is to implement information technology based tools to create and use a holistic reference database specific to intracranial aneurysms (IA). The SwissNeuroFoundation AneurysmDataBase are concerned with generating the data with which to populate this database. The purpose for populating the database are to: * Screen for and evaluate markers of risk for intracranial aneurysm formation and aneurysm rupture. Are considered as markers the following: genetics factors, microbiota, environmental factors, congenital factors (ie: cerebrovascular anatomical variants), transcriptomics signature, proteomics signature,shape characteristics, haemodynamics characteristics. * Screen for and evaluate prognostic factors of outcome regarding different management strategies including watchful observation, microsurgical treatment, endovascular treatment or any combination thereof. * Implement and evaluate patient-specific management protocols integrating all available information. * Evaluate the impact of the database and use of tools to improve care, reduce costs, support knowledge discovery and promote new industrial developments.

@neurIST : Informatique biomédicale intégrée Pour la Gestion Des anévrismes cérébraux

@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms

Condition
Intracranial Aneurysm
Intervention / Treatment

-

Contacts and Locations

San Francisco

University of California, San Francisco, California, United States,

Cincinnati

University of Cincinnati College of Medicine, Cincinnati, Ohio, United States,

Virginia Beach

University of Virginia, Virginia Beach, Virginia, United States,

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * able to provide consent or, in the event that a patient is incapable of providing consent, that a person is legally authorized to do so on behalf of the patient according to legal and ethical requirements of the country where the clinical centre is located.
  • * must have an angiographically proven intracranial aneurysm (MRA\< CTA\< DSA accepted).The determination of SAH requires the presence of a subarachnoid haemorrhage be verified on CT or by lumbar puncture.
  • * failure of a candidate to contribute clinical data,
  • * refusal to provide informed consent.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University Hospital, Geneva,

Philippe Bijlenga, PD MD PhD, PRINCIPAL_INVESTIGATOR, Geneva University

Sandrine Morel, PD PhD, STUDY_CHAIR, Hôpitaux Universitaire de Genève

Study Record Dates

2040-03-01