Patient-driven Management of BP in CKD

Description

The proposed research will evaluate if patients managing their blood pressure medications under the guidance of a clinical pharmacist works better to lower blood pressure than patients monitoring their blood pressure at home and the standard care. 60 Veterans with chronic kidney disease (CKD) will be included in the study. The study will further evaluate factors that may influence the Veteran to accept the self-management approach and what factors in the VHA healthcare system affect the implementation of the self-management approach.

Conditions

Chronic Kidney Disease

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Study Overview

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Study Details

Study overview

The proposed research will evaluate if patients managing their blood pressure medications under the guidance of a clinical pharmacist works better to lower blood pressure than patients monitoring their blood pressure at home and the standard care. 60 Veterans with chronic kidney disease (CKD) will be included in the study. The study will further evaluate factors that may influence the Veteran to accept the self-management approach and what factors in the VHA healthcare system affect the implementation of the self-management approach.

Pharmacist-guided, Patient-driven Management of High Blood Pressure in CKD: A Novel Approach

Patient-driven Management of BP in CKD

Condition
Chronic Kidney Disease
Intervention / Treatment

-

Contacts and Locations

Iowa City

Iowa City VA Health Care System, Iowa City, IA, Iowa City, Iowa, United States, 52246-2292

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age \>= 18 years,
  • * CKD stage 3 or 4 (estimated GFR: 15-59 mL/min/1.73m2) or
  • * Stage 2 CKD (estimated GFR 60-89 mL/min/1.73m2) with urinary albumin/creatinine ratio (ACR 300 mg/g if no DM and 30 mg/g if with DM), and
  • * Uncontrolled hypertension defined as the avg of 2 readings \> 140 systolic.
  • * Severely uncontrolled hypertension defined as systolic BP \>180,
  • * Patients with resistant hypertension and taking 4 BP medications,
  • * Orthostatic hypotension defined as reduced systolic BP by 20 mmHg or diastolic BP by 10 mmHg after 3 minutes of standing,
  • * Severe CKD defined as estimated GFR \< 20 mL/min/1.73m2,
  • * Life expectancy \<1 year,
  • * Severe liver disease,
  • * Severe congestive heart failure,
  • * Severe cognitive decline due to dementia,
  • * Pregnant, breastfeeding, or unwilling to use adequate birth control

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

VA Office of Research and Development,

Diana Jalal, MD, PRINCIPAL_INVESTIGATOR, Iowa City VA Health Care System, Iowa City, IA

Study Record Dates

2026-11-20