Study Overview
This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.
Description
The participants are being asked to take part in this clinical trial, a type of research study, because the participants are scheduled to receive or have recently received a hematopoietic cell transplant (HCT) or a solid organ transplant (SOT).
Primary Objective
To determine if pre-transplant screening for respiratory viral load predicts RVI within 1- year post-transplant among survivors.
Secondary Objectives:
* To develop and validate a classifier based on pre-transplant immunological profile predictive of developing an acute respiratory viral infection (aRVI), with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors.
* To develop and validate a classifier based on Day +100 post-transplant immunological profiles predictive of developing an acute respiratory viral infection (aRVI),with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors .
Official Title
Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients
Quick Facts
Study Start:2022-12-13
Study Completion:2029-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
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Contacts and Locations
Study Locations (Sites)
University of Alabama at Birmingham's (UAB)
Birmingham, Alabama, 35294
United States
Arkansas Children's Hospital
Little Rock, Arkansas, 72202
United States
Children's National Medical
Washington, District of Columbia, 20010
United States
University if Miami
Miami, Florida, 33146
United States
Emory and Children's Healthcare of Atlanta
Atlanta, Georgia, 30322
United States
University of Chicago Medicine Comer Children's Hospital
Chicago, Illinois, 60637
United States
Boston Children's Hospital
Boston, Massachusetts, 02115
United States
C.S. Mott Children's Hospital
Ann Arbor, Michigan, 48109
United States
Children's Hospital of Michigan
Detroit, Michigan, 48201
United States
University of Minnesota
Minneapolis, Minnesota, 55455
United States
Washington University
Saint Louis, Missouri, 63105
United States
University of Nebraska Medical Center
Omaha, Nebraska, 68198
United States
The Children's Hospital at Montefiore
Bronx, New York, 10467
United States
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229
United States
Nationwide Children's Hospital
Columbus, Ohio, 43205
United States
UPMC
Pittsburgh, Pennsylvania, 15224
United States
Medical University of South Carolina
Charleston, South Carolina, 29425
United States
Le Bonheur Children's Hospital
Memphis, Tennessee, 38103
United States
St. Jude Children's Research Hospital
Memphis, Tennessee, 38105
United States
UT Le Bonheur
Memphis, Tennessee, 38105
United States
Cook Children's
Fort Worth, Texas, 76104
United States
Baylor College of Medicine
Houston, Texas, 77030
United States
MD Anderson Center Center
Houston, Texas, 77030
United States
UTHealth Houston
Houston, Texas, 77225-0036
United States
Seattle Childrens
Seattle, Washington, 98105
United States
Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226
United States
Collaborators and Investigators
Sponsor: Arkansas Children's Hospital Research Institute
- Gabriela Maron, MD, PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital
- William J. Steinbach, MD, PRINCIPAL_INVESTIGATOR, Arkansas Children's Hospital Research Institute
Study Record Dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
Study Start Date2022-12-13
Study Completion Date2029-08
Study Record Updates
Study Start Date2022-12-13
Study Completion Date2029-08
Terms related to this study
Additional Relevant MeSH Terms
- Hematopoietic Cell Transplant
- Solid Organ Transplant
- Respiratory Viral Infection