The participants are being asked to take part in this clinical trial, a type of research study, because the participants are scheduled to receive or have recently received a hematopoietic cell transplant (HCT) or a solid organ transplant (SOT). Primary Objective To determine if pre-transplant screening for respiratory viral load predicts RVI within 1- year post-transplant among survivors. Secondary Objectives: * To develop and validate a classifier based on pre-transplant immunological profile predictive of developing an acute respiratory viral infection (aRVI), with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors. * To develop and validate a classifier based on Day +100 post-transplant immunological profiles predictive of developing an acute respiratory viral infection (aRVI),with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors .
Hematopoietic Cell Transplant, Solid Organ Transplant, Respiratory Viral Infection
The participants are being asked to take part in this clinical trial, a type of research study, because the participants are scheduled to receive or have recently received a hematopoietic cell transplant (HCT) or a solid organ transplant (SOT). Primary Objective To determine if pre-transplant screening for respiratory viral load predicts RVI within 1- year post-transplant among survivors. Secondary Objectives: * To develop and validate a classifier based on pre-transplant immunological profile predictive of developing an acute respiratory viral infection (aRVI), with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors. * To develop and validate a classifier based on Day +100 post-transplant immunological profiles predictive of developing an acute respiratory viral infection (aRVI),with RSV/PIV3/HMPV/SARS-CoV-2 through one-year post-transplant among survivors .
Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients
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University of Alabama at Birmingham's (UAB), Birmingham, Alabama, United States, 35294
Arkansas Children's Hospital, Little Rock, Arkansas, United States, 72202
Children's National Medical, Washington, District of Columbia, United States, 20010
University if Miami, Miami, Florida, United States, 33146
Emory and Children's Healthcare of Atlanta, Atlanta, Georgia, United States, 30322
University of Chicago Medicine Comer Children's Hospital, Chicago, Illinois, United States, 60637
Boston Children's Hospital, Boston, Massachusetts, United States, 02115
C.S. Mott Children's Hospital, Ann Arbor, Michigan, United States, 48109
Children's Hospital of Michigan, Detroit, Michigan, United States, 48201
University of Minnesota, Minneapolis, Minnesota, United States, 55455
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
to 18 Years
ALL
No
Arkansas Children's Hospital Research Institute,
Gabriela Maron, MD, PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital
William J. Steinbach, MD, PRINCIPAL_INVESTIGATOR, Arkansas Children's Hospital Research Institute
2029-08