COMPLETED

Young Adult Eating Habits

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Most individuals with obesity become so before age 35 and adolescent's unhealthy dietary patterns, specifically high intake of ultra-processed foods and poor overall diet quality, may contribute to energy overconsumption and weight gain. The overall objective of this research is to establish proof-of-concept for altered reward processing measured by brain response to ultra-processed foods, an increase in ad libitum energy intake, and adverse effects on executive function in response to an ultra-processed diet (81% total energy) compared to a diet emphasizing minimally processed foods in individuals aged 18-25 years.

Official Title

Influence of Ultra-processed Foods on Reward Processing and Energy Intake

Quick Facts

Study Start:2023-03-10
Study Completion:2025-06-10
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT05550818

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 25 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age 18-25 years
  2. * Weight stable (+5 lbs) for previous 6 months
  3. * No plans to gain/lose weight or change physical activity level
  4. * Willing to pick up food daily and consume foods provided for two 14-day periods
  5. * Verbal and written informed consent
  6. * Unrestrained eater (TFEQ cognitive restraint score \<11)
  7. * No reported history of eating disorders
  8. * Sedentary to recreationally active
  9. * ADHD medications if same med \>3 months at time of study
  1. * BMI \>30 kg/m2
  2. * Endocrine disorders or other major chronic disease (e.g., type 2 diabetes, hypothyroidism, hypertension)
  3. * Pregnant or plans to become pregnant
  4. * Food allergies or aversions
  5. * Claustrophobia
  6. * History of head injury with loss of consciousness for more than 10 minutes
  7. * Contraindications to MRI: individuals with pacemaker, aneurysm clips, neurostimulators, cochlear implants, metal in eyes, steel worker, or other implants.

Contacts and Locations

Principal Investigator

Alexandra G DiFeliceantonio, PhD
PRINCIPAL_INVESTIGATOR
Virginia Polytechnic Institute and State University
Brenda M Davy, PhD, RDN
PRINCIPAL_INVESTIGATOR
Virginia Polytechnic Institute and State University

Study Locations (Sites)

Virginia Polytechnic Institute and State University
Blacksburg, Virginia, 24061
United States
Fralin Biomedical Research Institute at VTC
Roanoke, Virginia, 24016
United States

Collaborators and Investigators

Sponsor: Virginia Polytechnic Institute and State University

  • Alexandra G DiFeliceantonio, PhD, PRINCIPAL_INVESTIGATOR, Virginia Polytechnic Institute and State University
  • Brenda M Davy, PhD, RDN, PRINCIPAL_INVESTIGATOR, Virginia Polytechnic Institute and State University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-03-10
Study Completion Date2025-06-10

Study Record Updates

Study Start Date2023-03-10
Study Completion Date2025-06-10

Terms related to this study

Keywords Provided by Researchers

  • Ultra-processed food
  • Minimally-processed food
  • Executive Functioning
  • Eating Habits
  • Reward Sensitivity
  • Brain Activity
  • fMRI

Additional Relevant MeSH Terms

  • Eating Behavior
  • Eating Habit