More than 5 million patients are admitted to the intensive care unit every year in the United States; most of these patients experience profound sleep and circadian disruption. Promotion of circadian alignment (i.e., alignment of the body's clocks) would make it possible to strategically schedule behaviors such as sleep and eating at normal body clock times, which is predicted to improve sleep quality and metabolic function. This project will test the ability of a sleep chronobundle (i.e., sleep promotion and circadian treatment bundle) to normalize circadian alignment and subsequently test if this realignment also improves sleep and metabolism.
Critical Illness, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Unspecified
More than 5 million patients are admitted to the intensive care unit every year in the United States; most of these patients experience profound sleep and circadian disruption. Promotion of circadian alignment (i.e., alignment of the body's clocks) would make it possible to strategically schedule behaviors such as sleep and eating at normal body clock times, which is predicted to improve sleep quality and metabolic function. This project will test the ability of a sleep chronobundle (i.e., sleep promotion and circadian treatment bundle) to normalize circadian alignment and subsequently test if this realignment also improves sleep and metabolism.
Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle
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Yale New Haven Hospital Medical Intensive Care Unit (YNHH MICU) at St Raphael's Campus, New Haven, Connecticut, United States, 06520
Yale New Haven Hospital Medical Intensive Care Unit (YNHH MICU) at York Street, New Haven, Connecticut, United States, 06520
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18 Years to
ALL
No
Yale University,
Melissa P Knauert, MD, PhD, PRINCIPAL_INVESTIGATOR, Yale University
2028-06-29