A Virtually Delivered Exercise Intervention To Mitigate Cognitive Deficits From Radiotherapy In AYAs With Brain Tumors

Eligibility Criteria

• 1. Age 15-39 years old
• 2. Self-reported diagnosis of a primary benign or malignant brain tumor or confirmed diagnosis of primary benign or malignant brain tumor radiographically or pathologically when available (relapse or newly diagnosed)
• 3. Plans to receive CRT at MDACC or, if the participant has already started CRT, the participant is eligible if they are within 3 weeks of the start of CRT
• 4. Received appropriate physician clearance
• 5. Able to move arms and legs, and ambulate safely
• 6. Participant is insufficiently active (reports less than 150 minutes of planned moderate-vigorous intensity activity per week in the prior week)
• 7. Participants and/or guardians are willing and able to provide informed consent
• 8. Has a smartphone with available space to download additional apps
• 9. Does not have sensorimotor strip impairment as indicated by the clinical team
• 10. Has internet access
• 11. Can receive physical therapy because this is part of the standard of care
• 12. Participants and/or guardians are willing and able to provide informed consent for protocol PA18-0130 (Pediatric Energy Balance Data Repository Study), companion protocol for the Fitbit application/assessment.
• 1. Non-English speaking
• 2. Screen failure for exercise safety based on Physical Activity Readiness Questionnaire (PAR-Q).12
• 3. Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease
• 4. Recent fracture or acute musculoskeletal injury that precludes ability to participate in supervised exercise training sessions
• 5. Cognitive and/or major sensory deficits that would impede the completion of research activities and assessments as deemed by the clinical team.
• 6. Self-reported diagnosis of a metastatic brain tumor or confirmed diagnosis of a metastatic brain tumor radiographically or pathologically when available
• 7. Self-report of pregnancy
• 8. Currently enrolled in another physical activity or exercise intervention
• 9. Prisoners
• 10. Self-reported pregnancy status