Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

Description

The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global disruption of the blood-brain barrier detected at the time of the stroke is informative about the risk of post-stroke cognitive decline over the next 3 years.

Conditions

Ischemic Stroke

Study Overview

Study Details

Study overview

The goal of this study is to gain a better understanding of why some individuals who have suffered a stroke experience post-stroke cognitive decline. Specifically this study is testing whether global disruption of the blood-brain barrier detected at the time of the stroke is informative about the risk of post-stroke cognitive decline over the next 3 years.

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

Global Blood-Brain Barrier Disruption and Post-Stroke Cognitive Decline

Condition
Ischemic Stroke
Intervention / Treatment

-

Contacts and Locations

Baltimore

Johns Hopkins Hospital, Baltimore, Maryland, United States, 21287

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Acute ischemic stroke demonstrated on an MRI scan that includes perfusion imaging with an exogenous contrast agent
  • * Inability to perform telephone-based cognitive assessments

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Johns Hopkins University,

Richard Leigh, MD, PRINCIPAL_INVESTIGATOR, Johns Hopkins University

Study Record Dates

2027-04-01