Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative

Description

24 patients will be treated with a coronally positioned tunnel with AlloDerm RTM with or without the addition of Enamel Matrix Derivative to compare the baseline and 6-month changes in recession defect coverage, clinical attachment levels, amount of keratinized tissue width, and soft tissue thickness.

Conditions

Recession, Gingival

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Study Overview

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Study Details

Study overview

24 patients will be treated with a coronally positioned tunnel with AlloDerm RTM with or without the addition of Enamel Matrix Derivative to compare the baseline and 6-month changes in recession defect coverage, clinical attachment levels, amount of keratinized tissue width, and soft tissue thickness.

Root Coverage Using Acellular Dermal Matrix and a Coronally Positioned Tunnel With or Without Biologic Materials

Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative

Condition
Recession, Gingival
Intervention / Treatment

-

Contacts and Locations

Louisville

University of Louisville, Louisville, Kentucky, United States, 40202

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Presence of at least one Miller class 1 or 2 soft tissue recession defect \>3 mm on a non-molar tooth.
  • * Healthy patients, at least 18 years of age.
  • * Patient understands and signs an informed consent approved by the University of Louisville IRB.
  • * Patients with debilitating systemic diseases, diseases that significantly affect the periodontium, infectious diseases, or psychological problems that may interfere with treatment.
  • * Previous head and neck radiation or chemotherapy within the previous 12 months.
  • * Patients with known allergies to any of the materials used in the study, including systemic antibiotics.
  • * Patients that use tobacco products (smoking, smokeless tobacco, or electronic cigarettes).
  • * Patients with alcohol abuse problems.
  • * Patients requiring antibiotic prophylaxis for dental procedures.
  • * Cemento-enamel unction not identifiable.
  • * Root surface restorations at the recession site.
  • * Patients undergoing long-term steroid therapy.
  • * History of previous root coverage procedure, graft, or guided tissue regeneration involving the recession site.
  • * Pregnant or lactating patients.
  • * Patients who fail to maintain oral hygiene levels of at least 80% plaque-free surfaces.
  • * Patients who fail to complete the informed consent form.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Louisville,

Bindu Dukka, BDS, MSD, MPH, PRINCIPAL_INVESTIGATOR, Director, Graduate Periodontics, University of Louisville

Study Record Dates

2024-10-30