RECRUITING

Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The primary objectives of this study are to determine whether exercise training is an effective strategy for treatment of Long COVID and characterize the cardiorespiratory and autonomic physiology in these patients to precisely characterize mechanisms contributing to this syndrome.

Official Title

Physiological Underpinnings of Post-Acute Sequelae of SARS CoV-2 ("Long COVID") and Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity

Quick Facts

Study Start:2023-03-01
Study Completion:2027-10-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05566483

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Adults ≥18 years with documented history of COVID-19 infection and symptoms consistent with Long COVID lasting \>12 weeks after diagnosis.
  1. * History of cardiovascular/pulmonary disease prior to infection
  2. * COVID-related myocardial injury such as evidence of myocarditis
  3. * Deep vein thrombosis/pulmonary embolism following COVID-19 infection
  4. * Exercise intolerance resulting from conditions that are not related to cardiorespiratory or autonomic factors (e.g. osteoarthritis or other musculoskeletal diseases);
  5. * Dependency of supplemental oxygen following COVID infection due to cardiovascular and/or pulmonary complications following acute COVID infection

Contacts and Locations

Study Contact

William K Cornwell, III, MD
CONTACT
303-724-2085
william.cornwell@cuanschutz.edu

Study Locations (Sites)

University of Colorado Hospital
Aurora, Colorado, 80045
United States

Collaborators and Investigators

Sponsor: University of Colorado, Denver

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-03-01
Study Completion Date2027-10-31

Study Record Updates

Study Start Date2023-03-01
Study Completion Date2027-10-31

Terms related to this study

Keywords Provided by Researchers

  • Cardiopulmonary Rehabilitation
  • Long COVID

Additional Relevant MeSH Terms

  • Post-acute Sequelae of SARS-CoV-2 Infection