Pilot Study of Stomach Cancer Early Detection and Prevention With Endoscopy

Description

Screening esophagogastroduodenoscopy (EGD )provides three distinct opportunities to decrease gastric cancer (GC) morbidity and mortality. has potential to discover cancer in early stages before the onset of symptoms, leading to higher rates of survival. Second, premalignant lesions such as adenomatous polyps, intestinal metaplasia and dysplasia can be discovered and removed with local resection, akin to polypectomies during screening colonoscopies, preventing the development of cancer. Third, EGD discovery and treatment of active Helicobacter pylori (HP) infection of the stomach provides an opportunity for primary prevention of GC.

Conditions

Gastric Cancer

Study Overview

Study Details

Study overview

Screening esophagogastroduodenoscopy (EGD )provides three distinct opportunities to decrease gastric cancer (GC) morbidity and mortality. has potential to discover cancer in early stages before the onset of symptoms, leading to higher rates of survival. Second, premalignant lesions such as adenomatous polyps, intestinal metaplasia and dysplasia can be discovered and removed with local resection, akin to polypectomies during screening colonoscopies, preventing the development of cancer. Third, EGD discovery and treatment of active Helicobacter pylori (HP) infection of the stomach provides an opportunity for primary prevention of GC.

Primary Objective: The Primary Objective of the Study is to Evaluate the Acceptability and Feasibility of EGD-SC

Pilot Study of Stomach Cancer Early Detection and Prevention With Endoscopy

Condition
Gastric Cancer
Intervention / Treatment

-

Contacts and Locations

New Brunswick

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States, 08903

New Brunswick

RWJBarnabas Health, New Brunswick, New Jersey, United States, 08903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Have provided signed informed consent for the trial
  • * Aged =40 and =80 years at the time of informed consent
  • * Not planned to undergo EGD and not had EGD in the last five years
  • * Planned to undergo colonoscopy
  • * Half of the recruited subjects will be from high-risk groups
  • * Willing and able to comply with all aspects of the protocol
  • * Persons with total gastrectomy
  • * Persons with anatomic alteration that precludes EGD
  • * Medical conditions that substantially increase risks for EGD
  • * Had EGD in the last five years

Ages Eligible for Study

40 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Rutgers, The State University of New Jersey,

Haejin In, MD, PRINCIPAL_INVESTIGATOR, Rutgers Cancer Institute of New Jersey

Study Record Dates

2024-08-01