Home-based Digital Exercise Training Program to Improve Physical Function of Older Sepsis Survivors - HEAL Sepsis Trial

Description

Older sepsis survivors have poor physical function and need post-sepsis physical rehabilitation. Often times, sepsis survivors live far from research facilities and do not have access to rehabilitation services. Remotely delivered exercise intervention could be the key to improve physical function in this population. Therefore, the study proposes to recruit older sepsis survivors at discharge from the hospital to home and assign them to either exercise training or standard care.

Conditions

Exercise Program, Standard Care Control

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Study Overview

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Study Details

Study overview

Older sepsis survivors have poor physical function and need post-sepsis physical rehabilitation. Often times, sepsis survivors live far from research facilities and do not have access to rehabilitation services. Remotely delivered exercise intervention could be the key to improve physical function in this population. Therefore, the study proposes to recruit older sepsis survivors at discharge from the hospital to home and assign them to either exercise training or standard care.

Home-based Digital Exercise Training Program to Improve Physical Function of Older Sepsis Survivors - HEAL Sepsis Trial

Home-based Digital Exercise Training Program to Improve Physical Function of Older Sepsis Survivors - HEAL Sepsis Trial

Condition
Exercise Program
Intervention / Treatment

-

Contacts and Locations

Gainesville

UF Clinical and Translational Research Building, Gainesville, Florida, United States, 32611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Able to perform lower and upper-body movements
  • * Sepsis survivor
  • * Age 55 years and older
  • * SPPB ≤ 6
  • * Being discharged to home from the hospital after surviving sepsis
  • * Willingness to be randomized to either treatment or control group
  • * Willingness to participate in all study procedures
  • * Willingness to use the devices and technology in the study
  • * Failure to provide informed consent
  • * Pregnant
  • * Discharge to a long-term facility
  • * Involvement in a structured rehabilitation program
  • * Inability to perform lower or upper-body exercises (e.g. being in wheelchair)
  • * Severe cardiac disease, including NYHA Class III or IV congestive heart failure, clinically significant aortic stenosis, history of cardiac arrest, use of a cardiac defibrillator, or uncontrolled angina
  • * Significant cognitive impairment, including known dementia diagnosis or a Mini-Mental State Examination exam score \< 24
  • * Progressive, degenerative neurologic disease, e.g., Parkinson's Disease, multiple sclerosis
  • * Severe pulmonary disease, requiring either steroid pills or injections or the use of supplemental oxygen
  • * Simultaneous participation in another intervention trial
  • * Poor or no cellular internet service at the primary place of living.

Ages Eligible for Study

55 Years to 105 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Florida,

Robert Mankowski, PhD, PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

2024-12-31