Rectal Indomethacin to Prevent Acute Pancreatitis in EUS-FNA of Pancreatic Cysts

Description

The aim of this randomized trial is to compare the rate of post-procedure pancreatitis in patients undergoing EUS-FNA of pancreatic cysts; patients will receive either a single dose of indomethacin or placebo administered rectally, during EUS-FNA.

Conditions

Pancreatic Cyst, Pancreatitis, Acute

Study Overview

Study Details

Study overview

The aim of this randomized trial is to compare the rate of post-procedure pancreatitis in patients undergoing EUS-FNA of pancreatic cysts; patients will receive either a single dose of indomethacin or placebo administered rectally, during EUS-FNA.

Randomized Trial of Rectal Indomethacin to Prevent Acute Pancreatitis in Patients Undergoing Endoscopic Ultrasound-guided Fine Needle Aspiration of Pancreatic Cysts

Rectal Indomethacin to Prevent Acute Pancreatitis in EUS-FNA of Pancreatic Cysts

Condition
Pancreatic Cyst
Intervention / Treatment

-

Contacts and Locations

Orlando

Orlando Health, Orlando, Florida, United States, 32806

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age ≥ 18 years
  • * Suspected or confirmed pancreatic cyst seen on imaging, requiring EUS-FNA
  • * Unable to obtain consent from the participant or the participant's legally authorized representative (LAR)
  • * Intrauterine pregnancy
  • * Hypersensitivity reaction to Aspirin or NSAIDs
  • * Patients with known history of chronic pancreatitis
  • * Patients with known renal failure

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Orlando Health, Inc.,

Ji Young Bang, MD MPH, PRINCIPAL_INVESTIGATOR, Orlando Health, Digestive Health Institute

Study Record Dates

2025-12