RECRUITING

Expanding Medication-Assisted Therapies in Central Asia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Central Asia (CA) represents the most rapidly growing HIV epidemic region worldwide, concentrated in people who inject drugs (PWID) and their sexual partners, and scaling up opioid agonist therapies (OAT) in this region is the most cost-effective strategy to prevent new HIV infections, and more effective when combined with antiretroviral therapy (ART). The investigators propose to use the Network for the Improvement of Addiction Treatment (NIATx) implementation strategy to scale-up OAT in three diverse Central Asian countries (Kazakhstan, Kyrgyzstan, Tajikistan) and guided by the Exploration-Planning-Implementation-Sustainment (EPIS) framework. Understanding the trajectories of implementation and scale-up in this context may emerge through creating communities of practice, especially when cohesion and competence evolves, and may guide other healthcare delivery challenges in the region (e.g., HIV, TB); as well as build important regional expertise and understanding implementation trajectories should help support OAT program sustainability.

Official Title

Expanding Medication-Assisted Therapies in Central Asia

Quick Facts

Study Start:2023-08-07
Study Completion:2026-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05579470

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Quantitative surveys for PWID
  2. 1. 18 years or older
  3. 2. Meeting DSM-V criteria for opioid dependence
  4. 3. Be either treatment naïve and seeking OAT or be on OAT for \< 90 days
  5. 2. Organizational Assessments for OAT Delivery Staff
  6. 1. 18 years or older
  7. 2. Currently working as an OAT delivery professional at an OAT delivery site
  8. 3. Focus Groups (PWID on OAT)
  9. 1. 18 years or older
  10. 2. Meeting DSM-V criteria for opioid dependence
  11. 3. Be either treatment naïve and seeking OAT or be on OAT for \< 90 days
  12. 4. Focus Groups (PWID not on OAT)
  13. 1. 18 years or older
  14. 2. Meeting Diagnostic and Statistical Manual of Mental Disorders(DSM)-V criteria for opioid dependence
  15. 3. Be OAT naïve (defined as never having been on OAT or having not received treatment for \> 1 year)
  16. 5. Focus Groups (OAT delivery staff)
  17. 1. 18 years or older
  18. 2. Currently working as an OAT delivery professional at an OAT delivery site
  19. 1. 18 years or older
  20. 2. Currently assigned as a Chief Narcologist for an Oblast
  21. 1. 18 years or older
  22. 2. Authorized as a professional to work at an OAT delivery site
  1. * Not willing to provide consent

Contacts and Locations

Study Contact

Frederick L Altice, MD
CONTACT
203-623-2634
frederick.altice@yale.edu

Principal Investigator

Frederick L Altice, MD
PRINCIPAL_INVESTIGATOR
Yale University

Study Locations (Sites)

Yale University
New Haven, Connecticut, 06510
United States

Collaborators and Investigators

Sponsor: Yale University

  • Frederick L Altice, MD, PRINCIPAL_INVESTIGATOR, Yale University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-08-07
Study Completion Date2026-12-31

Study Record Updates

Study Start Date2023-08-07
Study Completion Date2026-12-31

Terms related to this study

Keywords Provided by Researchers

  • HIV
  • OUD
  • OAT
  • Central Asia

Additional Relevant MeSH Terms

  • Opioid Use Disorder