Effects of Head-of-Bed on Intracranial Pressure

Description

The purpose of this study is to evaluate how pressure inside the skull responds to position changes in patients with brain bleeds.

Conditions

Subarachnoid Hemorrhage, Aneurysmal

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Study Overview

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Study Details

Study overview

The purpose of this study is to evaluate how pressure inside the skull responds to position changes in patients with brain bleeds.

Response of Intracranial Pressure Based on Head-of-Bed Positioning in Aneurysmal Subarachnoid Hemorrhage

Effects of Head-of-Bed on Intracranial Pressure

Condition
Subarachnoid Hemorrhage, Aneurysmal
Intervention / Treatment

-

Contacts and Locations

Hershey

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States, 17033

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients with subarachnoid hemorrhage confirmed by CT scan, MRI, or cerebral angiogram
  • * Age ≥ 18 years old
  • * Patients with intracranial pressure monitoring device
  • * Patients with continuous arterial blood pressure monitoring
  • * The subject or legally authorized representative must be available and able to consent
  • * Intubated patients who are prone
  • * Patients with left ventricular ejection fraction \<20% as evidenced by echocardiogram previously documented at any time in the electronic medical record
  • * Patients with a diagnosis of pulmonary hypertension
  • * Patients with a diagnosis of cirrhosis and/or evidence of liver failure. Evidence of liver failure will be assessed by the presence of ascites, edema, abnormal lab values including low albumin, elevated PTT, elevated PT, elevated INR, or elevated bilirubin without another etiology, or MELD score \>8.
  • * Patients who are clinically unstable defined as those who are unable to lie flat for 30 minutes for any reason, patients on more than one continuous IV medications to increase blood pressure, or patients who are actively undergoing resuscitation.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Milton S. Hershey Medical Center,

Cain Dudek, BS, PRINCIPAL_INVESTIGATOR, Penn State Hershey Medical Center College of Medicine

Study Record Dates

2026-03