RECRUITING

Effects of Head-of-Bed on Intracranial Pressure

Conditions

Subarachnoid Hemorrhage, Aneurysmal Hemorrhage, Subarachnoid Intracranial Pressure

Quick Navigation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to evaluate how pressure inside the skull responds to position changes in patients with brain bleeds.

Official Title

Response of Intracranial Pressure Based on Head-of-Bed Positioning in Aneurysmal Subarachnoid Hemorrhage

Quick Facts

Study Start:2023-04-24

Study Completion:2026-03

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT05604404

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Patients with subarachnoid hemorrhage confirmed by CT scan, MRI, or cerebral angiogram * Age ≥ 18 years old * Patients with intracranial pressure monitoring device * Patients with continuous arterial blood pressure monitoring * The subject or legally authorized representative must be available and able to consent	* Intubated patients who are prone * Patients with left ventricular ejection fraction \<20% as evidenced by echocardiogram previously documented at any time in the electronic medical record * Patients with a diagnosis of pulmonary hypertension * Patients with a diagnosis of cirrhosis and/or evidence of liver failure. Evidence of liver failure will be assessed by the presence of ascites, edema, abnormal lab values including low albumin, elevated PTT, elevated PT, elevated INR, or elevated bilirubin without another etiology, or MELD score \>8. * Patients who are clinically unstable defined as those who are unable to lie flat for 30 minutes for any reason, patients on more than one continuous IV medications to increase blood pressure, or patients who are actively undergoing resuscitation.

Inclusion Criteria

Exclusion Criteria

* Patients with subarachnoid hemorrhage confirmed by CT scan, MRI, or cerebral angiogram
* Age ≥ 18 years old
* Patients with intracranial pressure monitoring device
* Patients with continuous arterial blood pressure monitoring
* The subject or legally authorized representative must be available and able to consent

* Intubated patients who are prone
* Patients with left ventricular ejection fraction \<20% as evidenced by echocardiogram previously documented at any time in the electronic medical record
* Patients with a diagnosis of pulmonary hypertension
* Patients with a diagnosis of cirrhosis and/or evidence of liver failure. Evidence of liver failure will be assessed by the presence of ascites, edema, abnormal lab values including low albumin, elevated PTT, elevated PT, elevated INR, or elevated bilirubin without another etiology, or MELD score \>8.
* Patients who are clinically unstable defined as those who are unable to lie flat for 30 minutes for any reason, patients on more than one continuous IV medications to increase blood pressure, or patients who are actively undergoing resuscitation.

Contacts and Locations

Study Contact

Hazard, M.D.

CONTACT

717-531-6597

shazard@pennstatehealth.psu.edu

Principal Investigator

Cain Dudek, BS

PRINCIPAL_INVESTIGATOR

Penn State Hershey Medical Center College of Medicine

Study Locations (Sites)

Penn State Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033

United States

Collaborators and Investigators

Sponsor: Milton S. Hershey Medical Center

Cain Dudek, BS, PRINCIPAL_INVESTIGATOR, Penn State Hershey Medical Center College of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-04-24

Study Completion Date2026-03

Study Record Updates

Study Start Date2023-04-24

Study Completion Date2026-03

Terms related to this study

Keywords Provided by Researchers

Hemorrhage, Subarachnoid
Intracranial Pressure

Additional Relevant MeSH Terms

Subarachnoid Hemorrhage, Aneurysmal