Influence of TMS on Attention Modulation

Description

The purpose of this study is to help understand how attention processes influence brain engagement during emotion and social cognition. The investigators also want to know if these processes are associated with drinking alcohol. Participation includes three study visits of about 2 hours each over approximately a month. The first visit involves a magnetic resonance imaging (MRI) scan and answering survey questions. Each of the next two visits will involve a session of transcranial magnetic stimulation (TMS, a non-invasive brain stimulation technique) followed by another MRI scan. People in the Auburn/Opelika area 19 or older are eligible to participate. People who drink alcohol and people who do not drink or don't drink very much are invited to participate.

Conditions

Drinking, Alcohol

Study Overview

Study Details

Study overview

The purpose of this study is to help understand how attention processes influence brain engagement during emotion and social cognition. The investigators also want to know if these processes are associated with drinking alcohol. Participation includes three study visits of about 2 hours each over approximately a month. The first visit involves a magnetic resonance imaging (MRI) scan and answering survey questions. Each of the next two visits will involve a session of transcranial magnetic stimulation (TMS, a non-invasive brain stimulation technique) followed by another MRI scan. People in the Auburn/Opelika area 19 or older are eligible to participate. People who drink alcohol and people who do not drink or don't drink very much are invited to participate.

A Combined Neurofeedback- TMS Intervention for Alcohol Use Disorder - Aim 2

Influence of TMS on Attention Modulation

Condition
Drinking, Alcohol
Intervention / Treatment

-

Contacts and Locations

Auburn

Auburn University, Auburn, Alabama, United States, 36849

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. Age 18 or Older
  • 1. MRI Contraindications
  • 1. Presence of metal in the body that would make having a 7T MRI unsafe (including facial tattoos)
  • 2. Claustrophobia, such that individual would be unable to stay in the MRI for up to 1 hr
  • 3. Hearing loss, including tinnitus, that might be made worse by MRI or TMS
  • 2. TMS Contraindications
  • 1. Has ever had a seizure, or has a family history of epilepsy
  • 2. Taking medications or substances that lower the seizure threshold\*
  • 3. Implanted devices that are in the head or rely on physiological signals
  • 4. History of neurological disease, such as stroke or brain tumor
  • 5. Head injury with loss of consciousness greater than 30 minutes
  • 6. Actively withdrawing from alcohol
  • 3. Family history of schizophrenia or presence of psychotic symptoms

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Auburn University,

Samantha J Fede, PhD, PRINCIPAL_INVESTIGATOR, Principal Investigator

Study Record Dates

2024-12-15