RECRUITING

A Study of Tooth Erosion in People With Esophagogastric Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The researchers are doing this study to find out more about what may lead to the loss of tooth enamel (the thin outer covering of the tooth) and how often it happens in people with esophagogastric cancer, colorectal cancer, pancreatic cancer, breast cancer, head and neck cancer, or non-small cell lung cancer, or a healthy volunteer.

Official Title

Pilot Study of Dental Erosion as a Non-invasive Biomarker of Esophagogastric Cancer

Quick Facts

Study Start:2022-11-03
Study Completion:2025-11
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05612048

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Subject is willing and able to provide written informed consent.
  2. * Patients with a history of esophagogastric, HNSCC, PDAC, CRC, or NSCLC or healthy controls
  3. * Patients must be able to fully comprehend and complete the survey and be willing to have pictures taken of their teeth with a camera or intra-oral camera.
  4. * Patients must be able to understand English language or have access to adequate translation services.
  5. * Age ≥ 18 years old.
  1. * Subjects without evaluable molars or with significant molar dental work precluding dentists from assessing enamel status, Note: evaluable is defined as having bilateral assessable mandibular molars, or erosions present in the remaining assessable quadrants.
  2. * For healthy controls only, patients cannot have a non-skin cancer history nor presenting for a procedure evaluating reflux symptoms.

Contacts and Locations

Study Contact

Steven Maron, MD
CONTACT
646-888-6780
marons@mskcc.org
Luis Diaz, MD
CONTACT
646-888-4641

Principal Investigator

Steven Maron, MD
PRINCIPAL_INVESTIGATOR
Memorial Sloan Kettering Cancer Center

Study Locations (Sites)

Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065
United States

Collaborators and Investigators

Sponsor: Memorial Sloan Kettering Cancer Center

  • Steven Maron, MD, PRINCIPAL_INVESTIGATOR, Memorial Sloan Kettering Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-11-03
Study Completion Date2025-11

Study Record Updates

Study Start Date2022-11-03
Study Completion Date2025-11

Terms related to this study

Keywords Provided by Researchers

  • Tooth erosion
  • GERD
  • Loss of tooth enamel
  • 22-370

Additional Relevant MeSH Terms

  • Esophagogastric Cancer