RECRUITING

Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Holmium Laser Enucleation of the Prostate (HoLEP) is a size-independent treatment option for benign prostatic hypertrophy (BPH) as recommended by the American Urological Association (AUA) Guidelines. Loop diuretics (furosemide) have been given historically during the morcellation portion of HoLEP to promote urine production in the post-operative setting and to minimize the impact of fluid absorption during long periods of morcellation. The intra-operative use of 20mg IV furosemide in perioperative HoLEP pathways has been propagated with the dissemination of HoLEP across North America without evidence to support its routine administration. With increasing surgical efficiency from improvements in laser and morcellator technology, the role of intra-operative furosemide is unknown. This study is designed to assess if there is a significant difference in same day discharge rates after Holmium Laser Enucleation of the Prostate (HoLEP) with and without IV furosemide. .

Official Title

Loop Diuretics During Morcellation to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)

Quick Facts

Study Start:2023-03-01
Study Completion:2024-08-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT05620784

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 89 Years
Sexes Eligible for Study:MALE
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Males 18 -89 undergoing HoLEP
  2. * Willing to sign the Informed Consent Form
  3. * Able to read, understand, and complete patient questionnaires.
  1. * Allergy or hypersensitivity to furosemide or other loop diuretic
  2. * Anuric patients or patients with liver failure
  3. * Patients having a concurrent ureteroscopy +/- laser lithotripsy, percutaneous nephrolithotomy, or non-urologic surgery at the time of their HoLEP
  4. * Anticipated need for perineal urethrostomy at the time of HoLEP
  5. * Patient not undergoing catheter removal and voiding trial at Northwestern Memorial Hospital

Contacts and Locations

Study Contact

Nicholas S Dean, MD
CONTACT
7806906285
nicholas.dean@northwestern.edu

Principal Investigator

Amy E Krambeck, MD
PRINCIPAL_INVESTIGATOR
Northwestern Medicine

Study Locations (Sites)

Northwestern University
Chicago, Illinois, 60611
United States

Collaborators and Investigators

Sponsor: Northwestern University

  • Amy E Krambeck, MD, PRINCIPAL_INVESTIGATOR, Northwestern Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-03-01
Study Completion Date2024-08-01

Study Record Updates

Study Start Date2023-03-01
Study Completion Date2024-08-01

Terms related to this study

Additional Relevant MeSH Terms

  • BPH With Urinary Obstruction
  • BPH
  • Hematuria
  • Same Day Discharge